Is Ale Gluten Free?
Most traditional ales contain gluten as they are typically made from barley, which is a gluten-containing grain. However, there are some gluten-free ales available on the market that are made from alternative grains like sorghum, rice, or millet, or that have had the gluten removed through special processes.

Rich in antioxidants: Ale contains polyphenols, which are powerful antioxidants that can help protect cells from damage.
May improve heart health: Moderate consumption may increase HDL (good) cholesterol and reduce the risk of cardiovascular diseases.
Potential cognitive benefits: Some studies suggest that moderate ale consumption might help reduce the risk of cognitive decline and dementia.
Source of B vitamins: Ale contains small amounts of B vitamins, including folate, niacin, riboflavin, and vitamin B6.
May strengthen bones: Silicon in ale may contribute to increased bone mineral density.
Potential diabetes management: Some research indicates that moderate consumption might help reduce the risk of type 2 diabetes.
Stress reduction: The mild sedative effect of ale may help reduce stress and anxiety when consumed in moderation.
Improved digestion: Ale can stimulate the production of gastric juices, potentially aiding digestion.
Social benefits: Moderate consumption in social settings may contribute to improved mental well-being and social connections.Note: These benefits are associated with moderate consumption. Excessive alcohol intake can lead to numerous health problems and negate any potential benefits.
Individuals with alcohol use disorders or those in recovery from alcohol addiction
Pregnant women or those trying to conceive
People taking medications that interact negatively with alcohol
Individuals with certain medical conditions, such as liver disease or pancreatitis
Those with a history of alcohol-related health problems
People who are operating vehicles or machinery
Individuals under the legal drinking age
Those with allergies or sensitivities to ingredients commonly found in ale
People with certain religious or cultural beliefs that prohibit alcohol consumption
Individuals on specific diets that restrict alcohol intake
Those who experience negative reactions to alcohol, such as severe hangovers or alcohol intoleranceRemember that this list is not exhaustive, and it’s always best to consult with a healthcare professional for personalized advice regarding alcohol consumption.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.