Is Aleve Gluten Free?
Aleve (naproxen) is generally considered gluten-free, as it does not contain wheat, barley, rye, or oats in its active ingredients. However, it’s always best to check the specific product packaging or consult with the manufacturer to confirm, as inactive ingredients can sometimes vary between different formulations or production batches.

Pain relief: Effective for various types of pain, including headaches, muscle aches, menstrual cramps, and arthritis pain
Fever reduction: Helps lower body temperature in cases of fever
Anti-inflammatory properties: Reduces inflammation in the body, which can help with conditions like arthritis and tendonitis
Long-lasting effects: Provides relief for up to 12 hours, longer than some other over-the-counter pain relievers
Dental pain management: Helps alleviate pain after dental procedures
Menstrual symptom relief: Eases cramps and other menstrual discomforts
Sports injury treatment: Aids in reducing pain and swelling from minor sports-related injuries
Osteoarthritis symptom management: Helps reduce pain and stiffness associated with osteoarthritis
Migraine relief: Can help alleviate migraine headache symptoms
Gout pain reduction: May help reduce pain during acute gout attacks
Bursitis treatment: Helps manage pain and inflammation in bursitisIt’s important to note that while Aleve can provide these benefits, it should be used as directed and under the guidance of a healthcare professional, especially for long-term use or pre-existing medical conditions.
People with a history of allergic reactions to naproxen or other NSAIDs
Individuals with a history of asthma, especially those who have had aspirin-induced asthma
People with stomach ulcers or a history of gastrointestinal bleeding
Those with liver disease or impaired liver function
Individuals with kidney disease or impaired kidney function
People with heart disease, high blood pressure, or a history of stroke
Those at risk for blood clots or bleeding disorders
Pregnant women, especially in the third trimester
Breastfeeding mothers
People about to undergo or recovering from heart bypass surgery
Individuals taking blood thinners or other medications that may interact with Aleve
Those with a history of alcohol abuse
People with fluid retention or edema
Individuals with systemic lupus erythematosus (SLE)
Elderly patients, who may be more susceptible to side effectsAlways consult with a healthcare professional before taking Aleve, especially if you have any pre-existing medical conditions or are taking other medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.