Generally, traditional Alfredo sauce is gluten-free as it’s typically made with butter, heavy cream, Parmesan cheese, and seasonings, which don’t contain gluten. However, some store-bought or restaurant versions may include additives or thickeners that contain gluten, so it’s always best to check the ingredients or ask about preparation methods if you have gluten sensitivities.

Source of calcium: Due to its dairy content (cream and Parmesan cheese), Alfredo sauce provides calcium, which is essential for bone health.
Protein content: The cheese in Alfredo sauce contributes some protein to your diet.
Energy source: The high fat and calorie content can provide quick energy, which may be beneficial for athletes or those with high energy needs.
Vitamin A: The cream in Alfredo sauce contains some vitamin A, which is important for eye health and immune function.
Mood booster: As a comfort food, Alfredo sauce may provide temporary psychological benefits for some people.It’s important to note that these potential benefits are minimal compared to the sauce’s high calorie and saturated fat content. Alfredo sauce should be consumed in moderation as part of a balanced diet. For those seeking healthier alternatives, there are lower-fat versions and plant-based options available.
People with lactose intolerance: Alfredo sauce contains dairy products that can cause digestive issues for those with lactose intolerance.
Individuals with dairy allergies: The dairy ingredients in Alfredo sauce can trigger allergic reactions in those with milk allergies.
People on a low-fat diet: Alfredo sauce is high in saturated fat, which may not align with low-fat dietary goals.
Those watching their calorie intake: The sauce is calorie-dense due to its high fat content.
Individuals with high cholesterol: The saturated fat in Alfredo sauce can contribute to increased cholesterol levels.
People with heart conditions: The high fat and sodium content may not be suitable for those managing heart health.
Individuals following a vegan or plant-based diet: Traditional Alfredo sauce contains animal products.
Those with gastrointestinal issues: The richness of the sauce may exacerbate symptoms for some people with digestive sensitivities.
People with a weakened immune system: If the sauce is not properly prepared or stored, it can pose a food safety risk.
Individuals on certain medications: Some medications may interact with high-fat foods, so it’s best to consult a healthcare provider.Remember, moderation is key for most people, and those with specific health concerns should consult their healthcare provider for personalized dietary advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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