Is All Pepperoni Gluten Free?
Not all pepperoni is gluten-free. While traditional pepperoni is usually made from pork and beef without gluten-containing ingredients, some manufacturers may add fillers or binders that contain gluten, so it’s important to check the label or contact the manufacturer to be certain.

Protein source: Pepperoni contains protein, which is essential for building and repairing tissues.
Vitamin B12: It provides some vitamin B12, which is important for nerve function and the formation of red blood cells.
Zinc: Pepperoni contains zinc, which supports immune function and wound healing.
Iron: It provides some iron, which is necessary for oxygen transport in the blood.It’s important to note that pepperoni is also:
High in saturated fat
High in sodium
Processed meat, which has been linked to increased health risks when consumed in large quantitiesFor a balanced diet, it’s recommended to consume pepperoni in moderation and prioritize whole, unprocessed foods for optimal health benefits.
Individuals with pork allergies
People with beef allergies (if the pepperoni contains beef)
Those following a vegetarian or vegan diet
Individuals with high cholesterol who are advised to limit saturated fat intake
People with hypertension or heart disease who need to limit sodium intake
Those with gastrointestinal sensitivities to spicy foods
Individuals following a low-fat diet for health reasons
People with certain religious dietary restrictions (e.g., those following Halal or Kosher diets)
Individuals with nitrate or nitrite sensitivities (as these are often used in curing pepperoni)
Those with specific food additive allergies that may be present in some pepperoni products
Pregnant women who are advised to avoid cured meats due to the risk of listeria
Young children, as pepperoni can be a choking hazard and is high in sodium and fatRemember, individual dietary needs can vary, so it’s always best to consult with a healthcare professional or nutritionist for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.