Ancient grains is a broad category that includes both gluten-containing and gluten-free grains. While some ancient grains like quinoa, amaranth, and teff are naturally gluten-free, others such as spelt, kamut, and einkorn contain gluten.

Higher nutrient content: Many ancient grains are rich in vitamins, minerals, and antioxidants
Increased fiber: They often contain more dietary fiber than modern refined grains
Better protein quality: Some ancient grains have a more complete amino acid profile
Lower glycemic index: They typically cause a slower, more stable rise in blood sugar levels
Gluten-free options: Many ancient grains are naturally gluten-free, suitable for those with celiac disease or gluten sensitivity
Heart health: Some ancient grains may help reduce cholesterol levels and lower the risk of heart disease
Weight management: The high fiber and protein content can promote feelings of fullness and aid in weight control
Digestive health: The fiber in ancient grains supports a healthy gut microbiome
Reduced inflammation: Some ancient grains have anti-inflammatory properties
Better blood sugar control: They may help improve insulin sensitivity and reduce the risk of type 2 diabetes
Antioxidant properties: Many ancient grains are rich in antioxidants that protect cells from damage
Improved bone health: Some ancient grains are good sources of minerals important for bone health, like calcium and magnesium
Supports brain function: Certain ancient grains contain nutrients that may support cognitive function and brain health
Celiac disease patients: Many ancient grains (like spelt, kamut, and farro) contain gluten and should be avoided by those with celiac disease.
Gluten-sensitive individuals: People with non-celiac gluten sensitivity may need to avoid gluten-containing ancient grains.
Those with grain allergies: Individuals allergic to specific grains should avoid those particular ancient grains.
People on low-carb diets: Ancient grains are high in carbohydrates and may not fit into very low-carb eating plans.
Individuals with certain digestive disorders: Some people with IBS or other digestive issues may have trouble digesting certain grains.
Those with diabetes (in some cases): Some ancient grains have a high glycemic index and may need to be limited for blood sugar management.
People with specific grain intolerances: Some may have intolerances to specific ancient grains and should avoid those.
Individuals on a Paleo diet: This diet typically excludes all grains, including ancient ones.
Those with phytic acid sensitivities: Ancient grains contain phytic acid, which can interfere with mineral absorption in sensitive individuals.
People with certain autoimmune conditions: Some autoimmune protocols recommend avoiding grains altogether.Always consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have health concerns or dietary restrictions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions