Is Apple Cider Vinegar Gluten Free?
Yes, apple cider vinegar is generally considered gluten-free. It is made from fermented apple juice, which does not contain gluten, making it safe for people with celiac disease or gluten sensitivity to consume.

May help lower blood sugar levels and manage diabetes
Could aid in weight loss and fat reduction
May improve heart health by lowering cholesterol and blood pressure
Possesses antimicrobial properties that can fight bacteria
May help with digestion and gut health
Could boost skin health when applied topically
May have anti-cancer properties (though more research is needed)
Could help reduce acid reflux and heartburn
May enhance nutrient absorption
Potentially boosts energy and reduces fatigue
Could help balance the body’s pH levels
May support a healthy immune system
Could aid in detoxification processes
Might help reduce inflammation in the body
Possibly supports liver health and functionIt’s important to note that while many of these benefits have some scientific backing, more research is often needed to confirm their efficacy. Always consult with a healthcare professional before using ACV as a supplement or treatment.
People with diabetes who are taking insulin or insulin-stimulating medications, as ACV may lower blood sugar levels
Individuals with chronic kidney disease or decreased kidney function
Those with digestive issues such as ulcers, heartburn, or GERD (gastroesophageal reflux disease)
People with osteoporosis or low bone density, as ACV may lower bone mineral density
Individuals taking diuretics or other medications that lower potassium levels
Those with allergies to apples or other fruits in the Rosaceae family
Pregnant or breastfeeding women (due to lack of research on safety)
People with tooth enamel erosion or sensitive teeth
Individuals taking certain medications, including: – Heart medications – Laxatives – Some antibiotics (like tetracycline)
Those with throat problems or difficulty swallowing
People with histamine intolerance or sensitivity
Individuals prone to electrolyte imbalancesIt’s always best to consult with a healthcare professional before adding Apple Cider Vinegar to your diet, especially if you have any pre-existing health conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.