Generally speaking, most traditional barbecue sauces are gluten-free as they typically don’t contain wheat, barley, or rye. However, it’s always important to check the label of specific brands or homemade recipes, as some may include gluten-containing ingredients like soy sauce or malt vinegar.

Source of antioxidants: Many barbecue sauces contain tomatoes, which are rich in lycopene, a powerful antioxidant.
Vitamin C: Tomato-based barbecue sauces can provide some vitamin C, which supports immune function.
Low in fat: Most barbecue sauces are low in fat, making them a healthier alternative to some other condiments.
Potential antimicrobial properties: Some ingredients like vinegar and garlic in barbecue sauce may have antimicrobial effects.
Capsaicin benefits: Spicy barbecue sauces containing chili peppers may offer pain-relieving and metabolism-boosting properties due to capsaicin.
Flavor enhancement: By adding flavor to lean proteins and vegetables, it can encourage consumption of these healthier foods.
Potential blood sugar regulation: Some studies suggest vinegar (common in barbecue sauce) may help regulate blood sugar levels.
Trace minerals: Depending on ingredients, barbecue sauce may contain small amounts of minerals like potassium and iron.
Potential digestive aid: Vinegar in barbecue sauce may support digestion.Remember that many barbecue sauces are high in sugar and sodium, so it’s important to consume them in moderation and choose healthier versions when possible.
People with diabetes or those monitoring their blood sugar, due to the high sugar content in many barbecue sauces
Individuals on a low-sodium diet, as barbecue sauce often contains high levels of salt
Those with acid reflux or GERD, as the acidic ingredients can trigger symptoms
People with tomato allergies, since tomatoes are a common base ingredient in many barbecue sauces
Individuals following a low-FODMAP diet, as some ingredients in barbecue sauce may be high in FODMAPs
Those on a strict ketogenic diet, due to the high carbohydrate content in most barbecue sauces
People with certain food intolerances or allergies, depending on the specific ingredients used in the sauce
Individuals trying to lose weight or maintain a calorie-restricted diet, as barbecue sauce can add extra calories
Those with inflammatory bowel diseases who find that spicy or acidic foods trigger symptoms
People following specific diets that restrict added sugars or processed condimentsRemember that the need to avoid barbecue sauce can vary based on individual health conditions, dietary restrictions, and the specific ingredients in different barbecue sauce recipes.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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