Is Barley Gluten Free?
Barley is not gluten-free. It contains a protein called hordein, which is a form of gluten and can trigger reactions in people with celiac disease or gluten sensitivity.

High in fiber, which aids digestion and promotes feelings of fullness
Rich in vitamins and minerals, including B vitamins, iron, magnesium, and selenium
Contains antioxidants that may help reduce inflammation and oxidative stress
May help lower cholesterol levels due to its beta-glucan content
Potentially beneficial for heart health by reducing risk factors for cardiovascular disease
Can help regulate blood sugar levels, making it beneficial for people with diabetes
Supports weight management due to its low calorie and high fiber content
Contains proteins and essential amino acids, contributing to muscle health
May improve gut health by promoting the growth of beneficial gut bacteria
Gluten-free varieties are available for those with celiac disease or gluten sensitivity
May help reduce the risk of certain types of cancer, particularly colon cancer
Supports bone health due to its phosphorus, calcium, and copper content
Can be beneficial for skin health due to its antioxidant properties
May help boost the immune system due to its nutrient profileRemember that while barley offers many potential health benefits, it’s always best to consult with a healthcare professional or nutritionist for personalized dietary advice.
People with celiac disease: Barley contains gluten, which can trigger severe reactions in those with celiac disease.
Individuals with gluten sensitivity or intolerance: Even without celiac disease, some people may experience discomfort from consuming gluten-containing grains like barley.
Those with wheat allergies: While barley isn’t wheat, there’s a possibility of cross-reactivity for some individuals with wheat allergies.
People following a low FODMAP diet: Barley is high in fructans, which can cause digestive issues for those with IBS or following a low FODMAP diet.
Individuals with barley allergies: Though rare, some people may have specific allergies to barley.
Those on a strict ketogenic or very low-carb diet: Barley is high in carbohydrates and may not fit into these dietary plans.
People with certain gastrointestinal conditions: Some individuals with inflammatory bowel diseases may need to limit or avoid barley, especially during flare-ups.
Those taking certain medications: In some cases, high-fiber foods like barley may interfere with the absorption of certain medications.
Individuals preparing for specific medical procedures: Doctors may advise avoiding high-fiber foods like barley before certain medical tests or surgeries.Always consult with a healthcare professional or registered dietitian for personalized advice regarding dietary restrictions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.