Yes, broccoli is naturally gluten-free. As a vegetable, broccoli does not contain any wheat, barley, rye, or other gluten-containing grains.

High in nutrients and low in calories
Rich in antioxidants, including vitamin C
May help reduce inflammation in the body
Contains compounds that may protect against certain types of cancer
Supports heart health by lowering cholesterol levels
High in fiber, which aids digestion and promotes feelings of fullness
May help regulate blood sugar levels
Supports bone health due to its vitamin K and calcium content
Promotes healthy brain function and may slow mental decline
Boosts immune system function
Contains compounds that support eye health
May help slow the aging process due to its antioxidant content
Supports healthy skin due to its vitamin C and other nutrients
Can contribute to weight management as part of a balanced diet
May help protect against stomach ulcers
Supports liver health and natural detoxification processes
People taking blood-thinning medications: Broccoli is high in vitamin K, which can interfere with blood-thinning medications like warfarin.
Individuals with thyroid problems: Broccoli contains goitrogens, which can interfere with thyroid function, especially if consumed raw and in large quantities.
Those with IBS or sensitive digestive systems: Some people may experience gas, bloating, or digestive discomfort when consuming broccoli, especially if eaten raw.
People with allergies to broccoli or other cruciferous vegetables: Although rare, some individuals may be allergic to broccoli.
Those prone to calcium oxalate kidney stones: Broccoli contains oxalates, which can contribute to kidney stone formation in susceptible individuals.
Individuals taking certain medications: Broccoli may interact with some medications, such as certain antibiotics or antacids.
People with GERD or acid reflux: Some individuals may experience increased symptoms when consuming broccoli.
Those on low-FODMAP diets: Broccoli is high in FODMAPs, which may need to be avoided by some people with digestive issues.It’s important to note that for most people, broccoli is a nutritious food. Anyone with concerns about consuming broccoli should consult with a healthcare professional or registered dietitian.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions