Is Caramel Coloring Gluten Free?
Generally speaking, caramel coloring is considered gluten-free as it is typically made from corn or sugar, not from gluten-containing grains. However, it’s always best to check with the manufacturer or read product labels carefully, especially if you have celiac disease or severe gluten sensitivity, as cross-contamination during production is possible in rare cases.

Caramel coloring is primarily used for aesthetic purposes in foods and beverages.
It is one of the oldest and most widely used food colorings.
Caramel coloring is generally recognized as safe (GRAS) by the FDA when used in small amounts.
It does not contribute any significant nutritional value to foods or drinks.
Some types of caramel coloring (class III and IV) may contain small amounts of 4-methylimidazole (4-MEI), which has been linked to cancer in animal studies at high doses.
The amounts of 4-MEI in foods and drinks are generally considered too low to pose a significant health risk, but some health organizations recommend limiting consumption.
Caramel coloring does not provide any known health benefits beyond its role as a food coloring agent.It’s important to note that while caramel coloring itself doesn’t offer health benefits, some foods that contain it may have other nutritional values unrelated to the coloring.
People with caramel allergies: Although rare, some individuals may be allergic to caramel coloring and should avoid it.
Those with sensitivities to sulfites: Some caramel colorings contain sulfites, which can trigger reactions in sensitive individuals.
People with celiac disease or gluten sensitivity: Some caramel colorings may contain gluten, so it’s important to check labels.
Individuals following a vegan diet: Certain types of caramel coloring may be derived from animal sources.
Those concerned about potential carcinogenic effects: Some studies have raised concerns about 4-methylimidazole (4-MEI), a byproduct in certain caramel colorings, though regulatory bodies generally consider it safe in typical amounts.
People with phenylketonuria (PKU): Some caramel colorings may contain phenylalanine, which should be avoided by those with PKU.
Individuals trying to reduce artificial additives in their diet: Those following a whole foods or clean eating approach may choose to avoid caramel coloring.
People with diabetes or watching their sugar intake: While caramel coloring itself doesn’t typically contain sugar, it’s often found in sugary foods and beverages.It’s important to note that for most people, caramel coloring in moderation is considered safe by food regulatory agencies.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
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This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.