Generally, pure caramel syrup is gluten-free as it’s typically made from sugar, water, and sometimes vanilla or other flavorings that don’t contain gluten. However, it’s always important to check the specific product’s label or contact the manufacturer to confirm, as some caramel syrups may contain additives or be produced in facilities that process gluten-containing ingredients, potentially leading to cross-contamination.
Caramel syrup is mainly composed of sugar and water, with added flavoring.
It is a source of quick energy due to its high sugar content.
It contains small amounts of minerals like calcium and potassium, but in negligible quantities.
It may provide a temporary mood boost due to the sugar content.
In very small amounts, it can be part of a balanced diet for those without health issues.It’s important to note that excessive consumption of caramel syrup can lead to negative health effects due to its high sugar content, including:
Weight gain
Increased risk of tooth decay
Potential blood sugar spikes
Contribution to the development of type 2 diabetes if consumed in large quantities regularlyFor health benefits, it’s better to focus on whole foods, fruits, vegetables, and other nutrient-dense options rather than sweeteners like caramel syrup.
Diabetics: Caramel syrup is high in sugar and can cause rapid spikes in blood glucose levels.
People with insulin resistance or prediabetes: They should be cautious due to the high sugar content.
Those trying to lose weight or maintain a healthy weight: Caramel syrup is calorie-dense and can contribute to weight gain.
Individuals with dental issues: The high sugar content can contribute to tooth decay and cavities.
People with fructose intolerance or malabsorption: Caramel syrup often contains fructose, which can cause digestive issues for these individuals.
Those with a sensitivity or allergy to caramel coloring: Some people may experience allergic reactions to the coloring used in caramel syrup.
Individuals following a low-carb or ketogenic diet: Caramel syrup is high in carbohydrates and can disrupt these dietary plans.
People with certain gastrointestinal conditions: The high sugar content may exacerbate symptoms of conditions like IBS or SIBO.
Those with a history of reactive hypoglycemia: The rapid rise and fall in blood sugar levels can trigger symptoms.
Individuals with certain types of cancer: Some cancers are thought to thrive on sugar, so limiting high-sugar foods may be recommended.Remember, it’s always best to consult with a healthcare professional or registered dietitian for personalized advice regarding your diet.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.