Is Cayenne Pepper Gluten Free?
Yes, cayenne pepper is naturally gluten-free. As a pure spice derived from dried and ground chili peppers, it does not contain any gluten-containing ingredients.

Boosts metabolism and may aid in weight loss
Reduces appetite, potentially helping with calorie control
Contains capsaicin, which has pain-relieving properties
May help lower blood pressure
Improves circulation by promoting blood flow
Supports digestive health by stimulating gastric juices
Has anti-inflammatory properties
May help reduce the risk of certain types of cancer
Rich in antioxidants, which fight free radicals in the body
Supports heart health by reducing cholesterol levels
May help clear congestion and relieve cold symptoms
Enhances the absorption of other nutrients
Potential to boost the immune system
May help regulate blood sugar levels
Could improve psoriasis symptoms when applied topically
May have anti-fungal properties
Supports detoxification processes in the bodyRemember to consult with a healthcare professional before using cayenne pepper for medicinal purposes, especially if you have any existing health conditions or are taking medications.
People with gastroesophageal reflux disease (GERD) or acid reflux
Those with irritable bowel syndrome (IBS) or sensitive digestive systems
Individuals with peptic ulcers or other gastrointestinal disorders
People with bleeding disorders or those taking blood-thinning medications
Individuals with low blood pressure or those taking medications to lower blood pressure
Pregnant women (in large amounts)
Breastfeeding mothers (may affect breast milk)
People allergic to nightshade plants (cayenne is part of this family)
Those with chronic heartburn
Individuals scheduled for surgery (due to its blood-thinning effects)
People with certain skin conditions that may be irritated by capsaicin
Those with hemorroids or anal fissures
Individuals with a known allergy or sensitivity to cayenne or capsaicin
Young children, due to their sensitive digestive systems
People taking certain medications that may interact with cayenne (e.g., ACE inhibitors, aspirin, blood thinners)It’s always best to consult with a healthcare professional before adding cayenne pepper to your diet, especially if you have any health concerns or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.