Chili itself is typically gluten-free, as its main ingredients (meat, beans, tomatoes, and spices) do not contain gluten. However, some chili recipes or pre-made mixes may include gluten-containing ingredients like wheat flour as a thickener or beer for flavor, so it’s important to check the specific recipe or product ingredients if you have gluten sensitivities.

Rich in vitamins and minerals: Contains vitamins A, C, and B6, as well as minerals like potassium and iron
High in protein: Especially when made with meat or beans, providing essential amino acids
Good source of fiber: Particularly when made with beans, promoting digestive health
Antioxidant properties: Due to ingredients like tomatoes (lycopene) and spices
May boost metabolism: Thanks to capsaicin in chili peppers, potentially aiding in weight management
Potential anti-inflammatory effects: From various spices and ingredients used
May improve heart health: Due to its combination of vegetables, lean proteins, and fiber
Can help clear sinuses: Spiciness may provide temporary relief from congestion
Supports immune function: Vitamin C content helps bolster the immune system
May have mood-enhancing effects: Capsaicin can trigger the release of endorphins
Potentially reduces cancer risk: Some studies suggest ingredients in chili may have anti-cancer properties
Can be low in calories: Depending on ingredients, it can be a nutritious, low-calorie meal optionRemember that the exact health benefits can vary based on the specific ingredients and preparation method used in the chili recipe.
Individuals with acid reflux or gastroesophageal reflux disease (GERD)
People with irritable bowel syndrome (IBS)
Those with peptic ulcers or gastritis
Individuals with hemorrhoids or anal fissures
People with a known allergy or sensitivity to nightshade vegetables
Those with chronic heartburn
Individuals with inflammatory bowel diseases like Crohn’s disease or ulcerative colitis
People recovering from certain gastrointestinal surgeries
Those with a low spice tolerance or sensitivity to capsaicin
Individuals taking certain medications that may interact with spicy foods
Pregnant women who experience increased heartburn (though moderate amounts are generally considered safe)
Young children, who may find spicy foods too intense
People with certain chronic pain conditions that may be exacerbated by spicy foods
Those with oral sores or mouth inflammationRemember, everyone’s tolerance and reaction to spicy foods can vary, so it’s best to consult with a healthcare professional if you have concerns about eating chili.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions