Generally speaking, pure chocolate is naturally gluten-free as it is made from cocoa beans, cocoa butter, and sugar, none of which contain gluten. However, some chocolate products may contain gluten due to added ingredients or cross-contamination during manufacturing, so it’s important to check labels carefully, especially for those with celiac disease or gluten sensitivity.

Rich in antioxidants, which help fight free radicals in the body
May improve heart health by lowering blood pressure and improving blood flow
Contains minerals like iron, magnesium, copper, and manganese
Potentially reduces the risk of stroke
May improve brain function and cognitive performance
Could help protect your skin from sun damage
May lower the risk of diabetes by improving insulin sensitivity
Contains compounds that could improve mood and reduce symptoms of depression
May help reduce inflammation in the body
Could lower cholesterol levels, particularly LDL (bad) cholesterol
Potentially reduces the risk of certain cancers due to its flavonoid content
May improve exercise performance by increasing nitric oxide production
Could help with weight management when consumed in moderation
Provides a quick energy boost
May improve dental health due to compounds that inhibit bacteria growthRemember that these benefits are primarily associated with dark chocolate with high cocoa content, and moderation is key as chocolate is also high in calories and sugar.
People with chocolate allergies
Individuals with caffeine sensitivity
Those with migraine headaches triggered by chocolate
People with gastroesophageal reflux disease (GERD)
Individuals with kidney stones (due to oxalate content)
Those with irritable bowel syndrome (IBS) who are sensitive to FODMAPs
People trying to manage their weight, as chocolate is high in calories
Individuals with diabetes, who should monitor their sugar intake
Those with acne that worsens with chocolate consumption
People with atrial fibrillation triggered by chocolate
Individuals taking certain medications that may interact with chocolate (e.g., MAO inhibitors)
Young children, due to the caffeine and sugar content
People with phenylketonuria (PKU), who must avoid phenylalanineRemember that the degree of restriction may vary depending on individual circumstances and the type of chocolate consumed. Always consult with a healthcare professional for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.