Is Cottonseed Oil Gluten Free?
Yes, cottonseed oil is gluten-free. As a pure oil extracted from cotton plants, it does not contain any gluten proteins, which are found in wheat, barley, and rye.

High in vitamin E: Cottonseed oil is a good source of vitamin E, an antioxidant that helps protect cells from damage caused by free radicals.
May help lower cholesterol: Some studies suggest that cottonseed oil may help reduce LDL (bad) cholesterol levels.
Contains healthy unsaturated fats: Cottonseed oil is primarily composed of polyunsaturated and monounsaturated fats, which are considered heart-healthy when consumed in moderation.
May improve insulin sensitivity: Some research indicates that cottonseed oil might help improve insulin sensitivity, potentially benefiting those with or at risk for type 2 diabetes.
Potential anti-inflammatory properties: The oil contains compounds that may have anti-inflammatory effects in the body.
May support heart health: The combination of unsaturated fats and potential cholesterol-lowering effects may contribute to better heart health.
Source of omega-6 fatty acids: Cottonseed oil is rich in linoleic acid, an essential omega-6 fatty acid that the body needs for various functions.
Potential antimicrobial properties: Some studies suggest that cottonseed oil may have antimicrobial effects against certain bacteria and fungi.
May aid in weight management: When used as part of a balanced diet, the unsaturated fats in cottonseed oil may help with feeling full and satisfied, potentially aiding in weight management.
Heat stable for cooking: Cottonseed oil has a high smoke point, making it suitable for high-heat cooking methods while retaining its nutritional properties.Remember to consume cottonseed oil, like all oils, in moderation as part of a balanced diet.
Individuals with a known allergy to cotton or cottonseed products
People with a history of cardiovascular disease, as cottonseed oil is high in saturated fats
Those trying to reduce their intake of omega-6 fatty acids, as cottonseed oil is rich in these
Individuals with concerns about pesticide exposure, as cotton crops are often heavily treated with pesticides
People following a low-fat diet, as cottonseed oil is high in calories and fat
Those with digestive sensitivities, as some people may experience gastrointestinal discomfort from cottonseed oil
Pregnant women, as there is limited research on the effects of cottonseed oil during pregnancy
Individuals with a history of hormone-sensitive cancers, as cottonseed oil contains trace amounts of gossypol, which can affect hormone levels
People with specific health conditions that require them to limit their fat intake
Those following certain religious or cultural dietary restrictions that prohibit the consumption of cottonseed oilIt’s always best to consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have any underlying health conditions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
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On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
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Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.