Yes, pure cranberry juice is naturally gluten-free as it is made solely from cranberries, which do not contain gluten. However, it’s important to check the label of any cranberry juice cocktail or blend, as these may contain added ingredients that could potentially include gluten.

Urinary Tract Health: May help prevent urinary tract infections (UTIs)
Antioxidant Properties: Rich in antioxidants that fight free radicals
Heart Health: May improve cholesterol levels and lower blood pressure
Dental Health: Can inhibit bacteria that cause tooth decay and gum disease
Immune System Support: High in vitamin C, which boosts immunity
Anti-Inflammatory Effects: May reduce inflammation in the body
Digestive Health: Can help prevent H. pylori bacteria growth in the stomach
Cancer Prevention: Some studies suggest it may help prevent certain types of cancer
Kidney Stone Prevention: May help reduce the risk of kidney stone formation
Skin Health: Antioxidants may contribute to healthier, younger-looking skin
Weight Management: Low in calories and may aid in weight loss efforts
Liver Health: May help protect the liver from damage
Blood Sugar Regulation: May help improve insulin sensitivity in some peopleRemember that while cranberry juice offers these potential benefits, it’s best consumed in moderation as part of a balanced diet. Always consult with a healthcare professional for personalized advice.
Those taking blood-thinning medications (e.g., warfarin): Cranberry juice may interact with these drugs and increase the risk of bleeding.
People with kidney stones: Cranberries are high in oxalates, which can contribute to kidney stone formation in susceptible individuals.
Individuals with a history of calcium oxalate kidney stones: The high oxalate content in cranberries may increase the risk of stone formation.
Those with gastric ulcers or acid reflux: The high acidity of cranberry juice may exacerbate these conditions.
People with diabetes: Unsweetened cranberry juice is very tart, and sweetened versions can be high in sugar, potentially affecting blood glucose levels.
Individuals taking certain medications: Cranberry juice may interact with some drugs, including certain antibiotics and medications metabolized by the liver.
Those allergic to cranberries or other berries: Although rare, some people may have allergic reactions to cranberries.
Pregnant women: Large amounts of cranberry juice may increase the risk of pregnancy complications, so moderation is advised.
People with aspirin sensitivity: Cranberries contain salicylic acid, which is similar to aspirin and may cause reactions in sensitive individuals.
Those with a history of recurrent urinary tract infections: While cranberry juice is often recommended for UTIs, some people may experience increased symptoms.Always consult with a healthcare professional before making significant changes to your diet, especially if you have underlying health conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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