Yes, dextrose is gluten-free. It is a simple sugar derived from corn or wheat that has been processed to remove all gluten-containing proteins, making it safe for people with celiac disease or gluten sensitivity to consume.

Quick energy source: Dextrose is rapidly absorbed by the body, providing a fast energy boost.
Treatment for hypoglycemia: It’s used to quickly raise blood sugar levels in cases of low blood sugar.
Medical applications: Used in intravenous solutions for hydration and as a calorie source for patients.
Improved muscle recovery: Can help replenish glycogen stores after intense workouts.
Calorie source: Provides calories for individuals needing to gain weight or maintain calorie intake.
Flavor enhancement: Used to enhance flavors in food and beverage products.
Extends shelf life: Acts as a preservative in some food products.
Fluid and electrolyte balance: Dextrose helps in maintaining fluid balance, especially in patients undergoing surgery or critical care
Calorie source for medical use: It is often used as a calorie source in hospitals for patients needing parenteral nutritionRemember that while dextrose has these benefits, it should be consumed in moderation as part of a balanced diet, especially for those monitoring their sugar intake.
People with diabetes or impaired glucose tolerance, as dextrose can rapidly increase blood sugar levels
Individuals with hyperglycemia (high blood sugar)
Those with hyperosmolar hyperglycemic nonketotic syndrome (HHNS)
People with known allergies or sensitivities to corn or corn products, as dextrose is often derived from corn
Individuals with galactose intolerance, glucose-galactose malabsorption, or sucrase-isomaltase deficiency
Patients with hypokalemia (low potassium levels), as dextrose can further lower potassium levels
Those with fluid or electrolyte imbalances
Individuals with congestive heart failure or severe kidney disease, who may be sensitive to fluid overload
People with thiamine deficiency, as administering dextrose without thiamine can precipitate or worsen Wernicke’s encephalopathy
Patients with head injuries or increased intracranial pressure, as dextrose can exacerbate cerebral edema
Those undergoing peritoneal dialysis with solutions containing dextrose
Individuals on certain medications that may interact with dextrose, such as some diabetes medicationsAlways consult with a healthcare professional before using dextrose, especially if you have any medical conditions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.