Is Diet Pepsi Gluten Free?
Yes, Diet Pepsi is generally considered gluten-free. The ingredients in Diet Pepsi do not contain any gluten-containing grains or derivatives, making it safe for most people with celiac disease or gluten sensitivity to consume.

Zero calories: Diet Pepsi can help reduce calorie intake for those trying to manage their weight.
No sugar: It doesn’t contain sugar, which can be beneficial for people monitoring their sugar intake, including those with diabetes.
Hydration: Like other non-caffeinated beverages, it can contribute to daily fluid intake.
Caffeine source: Diet Pepsi contains caffeine, which may provide a temporary energy boost and improved alertness.
Satisfies cravings: It can help satisfy cravings for sweet drinks without adding calories or sugar.However, it’s important to note that Diet Pepsi and other artificially sweetened beverages have been the subject of ongoing health debates. Some studies suggest potential negative effects of artificial sweeteners, and health experts generally recommend water as the healthiest beverage choice. Always consult with a healthcare professional for personalized dietary advice.
Individuals with phenylketonuria (PKU), as Diet Pepsi contains phenylalanine
People with a sensitivity or allergy to aspartame or other artificial sweeteners
Those trying to reduce their caffeine intake, as Diet Pepsi contains caffeine
Individuals with certain gastrointestinal issues, as artificial sweeteners can cause digestive discomfort in some people
Pregnant women, who are often advised to limit caffeine intake
People trying to reduce their intake of artificial ingredients and preservatives
Individuals with migraines that may be triggered by artificial sweeteners
Those with a history of bladder cancer, as some studies have suggested a potential link between artificial sweeteners and increased risk
People trying to break a soda habit or reduce their dependence on sweet-tasting drinks
Individuals with dental concerns, as the acidity in Diet Pepsi can contribute to tooth enamel erosion
Young children, as artificial sweeteners are generally not recommended for their developing bodiesRemember that while these are general guidelines, it’s always best to consult with a healthcare professional for personalized advice based on individual health conditions and concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.