Rice itself is naturally gluten-free. However, “enriched rice” may potentially contain gluten if the enrichment process involves adding ingredients that contain gluten, so it’s important to check the specific product’s ingredients list or look for a certified gluten-free label to be certain.

Improved B-vitamin intake: Enriched rice typically contains added thiamin (B1), riboflavin (B2), niacin (B3), and folic acid (B9).
Better energy metabolism: B-vitamins help convert food into energy more efficiently.
Reduced risk of birth defects: The added folic acid can help prevent neural tube defects in developing fetuses.
Improved cognitive function: B-vitamins, especially B12 (sometimes added), support brain health and cognitive function.
Enhanced immune system: Some enriched rice varieties include added iron, which supports a healthy immune system.
Reduced risk of anemia: The added iron can help prevent iron-deficiency anemia.
Improved nervous system health: B-vitamins contribute to maintaining a healthy nervous system.
Better skin health: Some B-vitamins, like niacin, contribute to healthy skin.
Increased fiber intake: Some enriched rice products may include added fiber, which aids digestion and promotes feelings of fullness.
Potential reduction in heart disease risk: Folic acid may help lower homocysteine levels, potentially reducing the risk of heart disease.
Enhanced cellular repair and growth: B-vitamins play a crucial role in cell metabolism and DNA synthesis.Remember that while enriched rice offers these benefits, it’s still important to maintain a balanced diet with a variety of whole foods for optimal nutrition.
People with celiac disease or gluten sensitivity (if the rice is enriched with barley or wheat-based nutrients)
Individuals with diabetes or prediabetes (due to its high glycemic index)
Those on a low-carb diet
People trying to lose weight (in large quantities)
Individuals with certain metabolic disorders that require limiting specific nutrients
Those with a history of arsenic-related health issues (as rice can contain trace amounts of arsenic)
People with certain kidney problems who need to limit phosphorus intake
Individuals following a whole foods or unprocessed diet
Those with specific nutrient sensitivities to the added vitamins and minerals
People on medication that interacts with certain added nutrients (always consult with a healthcare provider)
Individuals trying to avoid synthetic vitamins and minerals
Those with allergies to any of the added nutrientsRemember, it’s always best to consult with a healthcare professional or registered dietitian for personalized advice based on individual health conditions and dietary needs.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.