Is Enriched Wheat Flour Gluten Free?
No, enriched wheat flour is not gluten-free. Wheat flour naturally contains gluten, and the enrichment process does not remove the gluten proteins.

Increased iron content: Helps prevent anemia and supports overall blood health
Added folic acid: Important for pregnant women to prevent birth defects and supports cell growth
Enhanced B vitamins (thiamin, riboflavin, niacin): Aids in energy metabolism and nervous system function
Improved calcium content: Supports bone health and muscle function
Better vitamin D levels: Helps with calcium absorption and bone strength
Increased fiber (if whole wheat): Promotes digestive health and helps maintain healthy blood sugar levels
Source of carbohydrates: Provides energy for daily activities
May contain added vitamin E: Acts as an antioxidant and supports immune function
Potential for reduced risk of neural tube defects in newborns due to folic acid fortification
Can help meet daily recommended intake of certain vitamins and minerals
May contribute to improved overall nutritional status in populations with limited access to diverse food sourcesIt’s important to note that while enriched wheat flour offers these benefits, whole grain flours are generally considered more nutritious as they retain more of their natural nutrients and fiber.
People with celiac disease
Individuals with non-celiac gluten sensitivity
Those with wheat allergies
People following a gluten-free diet for medical reasons
Individuals with certain autoimmune disorders who may benefit from a gluten-free diet
Those with irritable bowel syndrome (IBS) who find that wheat products trigger symptoms
People following specific low-carb diets, such as the ketogenic diet
Individuals trying to reduce their intake of refined carbohydrates for health reasons
Those with diabetes who are closely monitoring their carbohydrate intake
People with certain nutrient absorption issues, who may benefit from whole grain alternatives
Individuals following a paleo or primal diet
Those with specific religious or cultural dietary restrictions that exclude wheat products
People aiming to reduce their consumption of processed foodsIt’s important to note that for many of these groups, the avoidance of enriched wheat flour is part of a broader dietary strategy, and individuals should consult with a healthcare professional or registered dietitian before making significant changes to their diet.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.