Is Granulated Sugar Gluten Free?
Yes, granulated sugar is naturally gluten-free. Pure sugar is derived from either sugar cane or sugar beets, neither of which contain gluten.
Quick energy source: Sugar provides rapid energy in the form of simple carbohydrates.
Mood boost: Sugar consumption can temporarily elevate mood due to its effect on dopamine release.
Preservative: Sugar can act as a natural preservative in foods, helping to prevent spoilage.
Wound healing: In some medical settings, sugar paste is used topically to aid in wound healing due to its antimicrobial properties.
Electrolyte balance: In specific situations (e.g., treating hypoglycemia), sugar can help restore blood glucose levels.
Palatability: Sugar can make certain nutritious foods more palatable, potentially increasing the consumption of healthy items.It’s important to note that these points do not outweigh the potential negative health effects of excessive sugar consumption. Most health organizations recommend limiting added sugar intake as part of a balanced diet.
People with diabetes or prediabetes
Individuals struggling with obesity or trying to lose weight
Those with metabolic syndrome
People with heart disease or at high risk for cardiovascular problems
Individuals with non-alcoholic fatty liver disease (NAFLD)
Those with dental issues or at high risk for tooth decay
People with inflammatory conditions, as sugar can increase inflammation
Individuals with candida overgrowth or frequent yeast infections
Those with attention deficit hyperactivity disorder (ADHD), as sugar may worsen symptoms
People with certain types of cancer, as some cancer cells feed on sugar
Individuals with polycystic ovary syndrome (PCOS)
Those with a history of addiction, as sugar can be addictive for some people
People following specific diets like ketogenic or low-carb diets
Individuals with irritable bowel syndrome (IBS) or other digestive issues that may be exacerbated by sugar. Remember, while these groups should be especially cautious, it’s generally recommended for everyone to limit their intake of added sugars for optimal health.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.