Is Grape Juice Gluten Free?
Yes, grape juice is naturally gluten-free as it is made from grapes, which do not contain gluten. However, it’s always wise to check the label of commercially produced grape juices to ensure no gluten-containing additives or flavorings have been added during processing.

Rich in antioxidants, particularly resveratrol and flavonoids
May help lower blood pressure
Supports heart health by improving cholesterol levels
Potentially reduces the risk of blood clots
May boost brain function and cognitive performance
Supports immune system function
Contains anti-inflammatory properties
May help improve bone strength
Provides a good source of vitamins C and K
Aids in hydration due to high water content
May help reduce the risk of certain types of cancer
Supports eye health due to lutein and zeaxanthin content
Can contribute to better sleep quality
May help in maintaining healthy skin
Supports digestive health due to fiber content (if pulp is included)
Potentially helps in managing blood sugar levelsRemember that while grape juice offers these potential benefits, it’s also high in natural sugars, so moderation is key, especially for those monitoring their sugar intake.
People with diabetes or blood sugar issues, due to its high sugar content
Individuals taking blood-thinning medications like warfarin, as grape juice can interact with these drugs
Those with grape allergies or sensitivities
People with acid reflux or GERD, as the acidity may worsen symptoms
Individuals on certain medications that interact with grapefruit juice, as grape juice may have similar effects
Those trying to lose weight, due to its high calorie content
People with kidney problems, as grape juice is high in potassium
Individuals with a history of kidney stones, particularly calcium oxalate stones
Those with fructose intolerance or malabsorption
Young children, as excessive juice consumption can lead to dental issues and poor nutrition
People with sulfite sensitivities, as some grape juices contain added sulfitesAlways consult with a healthcare professional for personalized advice regarding dietary restrictions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.