Is Grapeseed Oil Gluten Free?
Yes, grapeseed oil is naturally gluten-free. It is derived from grape seeds and does not contain any gluten-containing ingredients or come into contact with gluten during processing, making it safe for those with celiac disease or gluten sensitivity.

Rich in antioxidants, particularly vitamin E and flavonoids
May help reduce inflammation in the body
Potentially lowers cholesterol levels
May improve heart health by reducing the risk of blood clots
Contains high levels of linoleic acid, an omega-6 fatty acid essential for health
Might aid in maintaining healthy skin by promoting collagen production
Could help regulate blood sugar levels
May support immune system function
Potentially beneficial for cognitive health and brain function
Could assist in weight management due to its high PUFA content
May have antimicrobial properties
Possibly helps in reducing the risk of certain types of cancer (though more research is needed)
Can be used as a healthier alternative to other cooking oils due to its high smoke point
May contribute to better bone health
Could help in managing hormonal imbalances in some casesRemember that while these benefits are supported by various studies, more research is needed in some areas, and it’s always best to consult with a healthcare professional before making significant dietary changes.
People with grape allergies: Those allergic to grapes may also react to grapeseed oil.
Individuals taking blood thinners: Grapeseed oil may interact with medications like warfarin, potentially increasing bleeding risk.
People with bleeding disorders: Due to its potential blood-thinning properties, those with bleeding disorders should consult a doctor before using grapeseed oil.
Individuals scheduled for surgery: It’s advisable to stop using grapeseed oil at least two weeks before surgery due to its potential blood-thinning effects.
Those with low blood pressure: Grapeseed oil may lower blood pressure, so individuals with already low blood pressure should use caution.
People with hormone-sensitive conditions: Grapeseed oil contains compounds that may act like estrogen, potentially affecting hormone-sensitive conditions.
Individuals with liver disease: Some studies suggest that grapeseed oil may affect liver function, so those with liver issues should consult a doctor before use.
Pregnant or breastfeeding women: There’s limited research on the safety of grapeseed oil during pregnancy or breastfeeding, so it’s best to consult a healthcare provider.Always consult with a healthcare professional before making significant changes to your diet or supplement regimen, especially if you have pre-existing health conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.