Is Hemp Gluten Free?
Yes, hemp is naturally gluten-free. Hemp seeds, hemp protein, and other hemp-derived products do not contain gluten, making them safe for people with celiac disease or gluten sensitivity.

Rich source of plant-based protein
High in essential fatty acids (omega-3 and omega-6)
Contains all nine essential amino acids
Good source of dietary fiber
Abundant in vitamins and minerals (including vitamin E, magnesium, phosphorus, and potassium)
May help reduce inflammation in the body
Potential to lower blood pressure
May aid in heart health by reducing cholesterol levels
Could help balance hormones
Possible neuroprotective properties
May assist in relieving symptoms of PMS and menopause
Potential to improve skin health
Could aid in digestion and gut health
May help in managing blood sugar levels
Possible benefits for joint health and arthritis symptoms
Potential to boost immune system function
May help in reducing anxiety and promoting better sleepRemember that while hemp has many potential benefits, more research is needed to fully understand its effects. Always consult with a healthcare professional before making significant changes to your diet or health regimen.
Pregnant women: Due to limited research on the effects of hemp on fetal development.
Breastfeeding mothers: As hemp compounds can pass through breast milk.
Individuals with liver disease or impaired liver function: Hemp may affect liver enzyme levels.
People taking medications: Hemp can interact with various medications, including blood thinners and some seizure medications.
Those with a history of substance abuse: Particularly if the hemp product contains THC.
Individuals with allergies to cannabis or related plants: To avoid potential allergic reactions.
People with certain mental health conditions: Such as bipolar disorder or schizophrenia, as hemp might exacerbate symptoms.
Children and adolescents: Unless under medical supervision, due to potential effects on brain development.
Individuals scheduled for surgery: Hemp may interact with anesthesia and affect blood clotting.
Those with low blood pressure: Hemp might further lower blood pressure.
People with hormonal imbalances: Hemp can potentially affect hormone levels.Always consult with a healthcare professional before using hemp products, especially if you have any pre-existing health conditions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.