Is Hoisin Gluten Free?
Traditional hoisin sauce typically contains wheat flour, which contains gluten, making it not gluten-free. However, there are some gluten-free versions of hoisin sauce available on the market, made with alternative ingredients like rice flour or tamari instead of wheat-based soy sauce.

Low in calories: Hoisin sauce is relatively low in calories, making it a good option for those watching their calorie intake.
Contains some vitamins and minerals: It provides small amounts of iron, calcium, and potassium.
Antioxidant properties: Some ingredients in hoisin sauce, such as garlic and chili peppers, contain antioxidants that may help fight free radicals in the body.
Flavor enhancer: It can add flavor to dishes without the need for excessive salt or fat.
May have antimicrobial properties: Garlic, a common ingredient in hoisin sauce, has natural antimicrobial properties.
Could aid digestion: Some ingredients like vinegar may help stimulate digestive enzymes.
Potential anti-inflammatory effects: Certain components, like garlic and chili peppers, have anti-inflammatory properties.However, it’s important to note that hoisin sauce is typically high in sodium and sugar, so it should be consumed in moderation. The health benefits are limited and should not be overstated. As with any condiment, it’s best used as part of a balanced diet.
People with soy allergies: Hoisin sauce typically contains soybeans as a primary ingredient.
Individuals with wheat or gluten sensitivities: Many hoisin sauces contain wheat flour as a thickening agent.
Those on a low-sodium diet: Hoisin sauce is often high in sodium.
People with sesame allergies: Some hoisin sauce recipes include sesame oil or seeds.
Individuals watching their sugar intake: Hoisin sauce can be high in sugar content.
Those following a strict vegan diet: Some hoisin sauces may contain animal products like fish sauce.
People with garlic or onion sensitivities: Many hoisin sauce recipes include these ingredients.
Individuals with specific food colorings allergies: Some commercial hoisin sauces may contain artificial food coloring.
Those following a low FODMAP diet: Hoisin sauce contains high FODMAP ingredients.
People with sulfite sensitivities: Some hoisin sauces may contain sulfites as preservatives.Always check the ingredient list if you have specific dietary concerns or allergies, as ingredients can vary between brands and recipes.
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What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
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This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.