Is Homemade Sourdough Gluten Free?
Traditional homemade sourdough bread is not gluten-free, as it is typically made with wheat flour which contains gluten. However, it is possible to make gluten-free sourdough bread using alternative flours such as rice flour, buckwheat flour, or a gluten-free flour blend, but this would be a specific gluten-free variation and not the classic sourdough recipe.

Improved digestibility: The fermentation process breaks down gluten and phytic acid, making it easier to digest for some people.
Lower glycemic index: Sourdough bread typically has a lower glycemic index compared to regular bread, potentially helping with blood sugar control.
Prebiotic properties: The fermentation process creates prebiotic compounds that can support gut health and beneficial bacteria.
Enhanced nutrient absorption: The fermentation process can increase the bioavailability of nutrients like folate, iron, and zinc.
Potential probiotic benefits: Some sourdough breads may contain live probiotic cultures, which can support digestive health.
Reduced antinutrient content: Fermentation reduces phytates and enzyme inhibitors, which can interfere with nutrient absorption.
Longer shelf life: The acidity in sourdough bread helps prevent mold growth, reducing the need for artificial preservatives.
Lower sodium content: Homemade sourdough often contains less salt than commercial breads.
Possible reduced gluten sensitivity: Some people with mild gluten sensitivity may find sourdough easier to tolerate.
Rich in antioxidants: The fermentation process can increase antioxidant content in the bread.
Potential antimicrobial properties: The acidity in sourdough may help inhibit the growth of harmful bacteria.Remember that while sourdough offers these potential benefits, it’s still important to consume bread in moderation as part of a balanced diet.
People with celiac disease or non-celiac gluten sensitivity, as sourdough typically contains gluten
Individuals with yeast allergies, as sourdough contains wild yeast
Those on a low-carb or ketogenic diet, due to the bread’s high carbohydrate content
People with diabetes who need to carefully monitor their carbohydrate intake
Individuals following a low-FODMAP diet, as sourdough may still contain some fermentable carbohydrates
Those with severe wheat allergies
People on a strict low-sodium diet, as bread typically contains salt
Individuals with certain gastrointestinal conditions that require limiting fermented foods
Those following specific religious or cultural dietary restrictions that prohibit leavened bread
People with severe acid reflux or GERD who find that fermented foods exacerbate their symptoms
Individuals with candida overgrowth who are advised to avoid fermented products
Those on a raw food diet, as sourdough bread is cookedRemember that while some people may need to avoid sourdough, others might find it more digestible than regular bread. Always consult with a healthcare professional or registered dietitian for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.