Is Hops Gluten Free?
Hops themselves are naturally gluten-free, as they do not contain wheat, barley, rye, or other gluten-containing grains. However, when used in beer production, hops may come into contact with gluten-containing ingredients, so beer made with hops is typically not gluten-free unless specifically labeled as such.

Anti-inflammatory properties: May help reduce inflammation in the body
Anxiety and stress relief: Can promote relaxation and improve sleep quality
Antioxidant effects: Contains compounds that may protect cells from oxidative damage
Potential cancer-fighting properties: Some studies suggest hops may have anti-cancer effects
Estrogenic activity: May help alleviate menopausal symptoms in women
Digestive aid: Can stimulate gastric juices and aid in digestion
Antimicrobial properties: May help fight certain bacteria and fungi
Pain relief: Some compounds in hops may have analgesic effects
Cardiovascular health: May help lower cholesterol and improve heart health
Weight management: Some studies suggest hops may help reduce body fat
Bone health: May help improve bone density and reduce the risk of osteoporosis
Cognitive function: Potential neuroprotective effects that could benefit brain health
Skin health: Topical application may help with certain skin conditionsIt’s important to note that while these benefits have been observed in various studies, more research is needed to fully understand the effects of hops on human health. Always consult with a healthcare professional before using hops for medicinal purposes.
Pregnant women: Hops may have estrogenic effects and could potentially affect fetal development.
Breastfeeding mothers: The compounds in hops might pass through breast milk to the infant.
People with estrogen-sensitive conditions: Such as certain types of breast cancer, uterine cancer, or endometriosis.
Those with depression: Hops can have sedative effects and may worsen symptoms of depression.
Individuals taking sedative medications: Hops may increase drowsiness and interact with these drugs.
People with allergies to plants in the Cannabaceae family: This includes cannabis and hemp.
Those with gluten sensitivities or celiac disease: If consuming hops in beer form, as most beers contain gluten.
Individuals with liver disease: Hops may affect liver function.
People taking certain medications: Hops can interact with various drugs, including those metabolized by the liver.
Those scheduled for surgery: Hops may increase bleeding risk and interact with anesthesia.
Individuals with a history of night terrors: Hops might exacerbate this condition in some people.Always consult with a healthcare provider before making significant changes to your diet or supplement regimen, especially if you have pre-existing health conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.