Most pure licorice root and licorice candy is naturally gluten-free. However, some licorice products may contain gluten due to added ingredients or manufacturing processes, so it’s always best to check the label or contact the manufacturer if you have celiac disease or gluten sensitivity.

Anti-inflammatory properties: Licorice contains compounds that can help reduce inflammation in the body.
Digestive health: It may help soothe stomach ulcers, reduce acid reflux, and alleviate indigestion.
Respiratory support: Licorice can help relieve symptoms of sore throat, coughs, and bronchitis.
Adrenal support: It may help balance cortisol levels and support adrenal gland function.
Skin health: Licorice has been used topically to treat eczema, psoriasis, and other skin conditions.
Immune system boost: It contains antioxidants that can help strengthen the immune system.
Oral health: Licorice may help prevent tooth decay and reduce the growth of cavity-causing bacteria.
Menopausal symptom relief: Some studies suggest it can help reduce hot flashes in menopausal women.
Potential anti-viral properties: Licorice has shown promise in fighting certain viruses in laboratory studies.
Blood sugar regulation: It may help improve insulin sensitivity and regulate blood sugar levels.
Liver health: Some research indicates licorice might have protective effects on the liver.Note: While licorice has potential health benefits, it can also have side effects and interact with certain medications. It’s important to consult with a healthcare professional before using licorice as a supplement or remedy.
Pregnant women, as it may increase the risk of preterm labor
Individuals with high blood pressure or hypertension
People with heart conditions or heart disease
Those with kidney problems or kidney disease
Individuals with liver disease
People taking certain medications, such as blood thinners, diuretics, or steroids
Those with low potassium levels (hypokalemia)
Individuals with hormone-sensitive conditions, such as breast cancer or endometriosis
People with diabetes, as licorice may affect blood sugar levels
Those with a history of seizures or epilepsy
Individuals with fluid retention or edema
People with cholestatic liver disorders or cirrhosis
Those allergic to licorice or any of its components
Individuals preparing for surgery (should stop consuming licorice at least two weeks prior)
People with gastrointestinal disorders like ulcers or inflammatory bowel diseaseAlways consult with a healthcare professional before consuming licorice, especially if you have any medical conditions or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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