Masa harina is typically gluten-free as it is made from corn that has been treated with lime water and then ground into a fine flour. However, it’s always important to check the label of the specific brand you’re using, as some manufacturers may process their masa harina in facilities that also handle wheat products, potentially leading to cross-contamination.

Gluten-free: Suitable for people with celiac disease or gluten sensitivity
Rich in complex carbohydrates: Provides sustained energy release
Good source of fiber: Aids digestion and promotes gut health
Contains essential minerals: Including iron, zinc, and magnesium
Low in fat: Beneficial for weight management and heart health
Source of antioxidants: Contains compounds that may help fight oxidative stress
Provides some protein: Contributes to muscle maintenance and growth
Low glycemic index: May help regulate blood sugar levels
Contains niacin (Vitamin B3): Supports nervous system function and energy metabolism
Source of calcium: When enriched, it can contribute to bone health
Contains folate: Important for cell growth and development, especially during pregnancy
Naturally low in sodium: Beneficial for maintaining healthy blood pressure
Preservative-free: When using traditional preparation methods
May have prebiotic properties: Can potentially support beneficial gut bacteriaRemember that the nutritional profile can vary depending on the specific brand and whether it’s enriched or not.
People with celiac disease or non-celiac gluten sensitivity: – Although Masa Harina is naturally gluten-free, cross-contamination during processing can occur. – Look for certified gluten-free Masa Harina if you have these conditions.
Individuals with corn allergies: – Masa Harina is made from corn, so those with corn allergies should avoid it.
People following a low-carb or ketogenic diet: – Masa Harina is high in carbohydrates and may not fit into these dietary plans.
Those with diabetes or blood sugar concerns: – Masa Harina can cause blood sugar spikes due to its high carbohydrate content.
Individuals with digestive issues: – Some people may find corn-based products difficult to digest.
People with a sensitivity to GMOs: – If concerned about genetically modified organisms, look for non-GMO certified Masa Harina.
Those watching their calorie intake: – Masa Harina is calorie-dense and may not be suitable for strict calorie-controlled diets.
Individuals with a sensitivity to phytic acid: – Masa Harina contains phytic acid, which can interfere with mineral absorption in some people.Remember, it’s always best to consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have specific health concerns or dietary restrictions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions