Mezcal, like other distilled spirits, is generally considered gluten-free. The distillation process removes gluten proteins, making mezcal safe for most people with celiac disease or gluten sensitivity to consume.

Rich in antioxidants: Mezcal contains compounds that may help fight free radicals in the body.
Potential digestive aid: Some believe it can help stimulate digestion and relieve stomach discomfort.
Possible probiotic properties: The fermentation process may introduce beneficial bacteria.
Low in calories: Compared to many other alcoholic beverages, mezcal is relatively low in calories.
May lower blood sugar: Some studies suggest it might help regulate blood sugar levels.
Potential stress reducer: Like other alcoholic beverages, it may help some people relax when consumed in moderation.
Source of minerals: Contains trace amounts of potassium, calcium, and magnesium.
Possible anti-inflammatory properties: Some compounds in mezcal may have anti-inflammatory effects.
Potential pain relief: Traditional uses include using mezcal for minor pain management.
May support heart health: Moderate consumption might have some cardiovascular benefits.Remember, these benefits are associated with moderate consumption. Excessive alcohol intake can lead to serious health problems. Always consult with a healthcare professional about alcohol consumption and its effects on your health.
Pregnant women
Individuals under the legal drinking age
People with alcohol addiction or a history of alcohol abuse
Those taking medications that interact negatively with alcohol
Individuals with liver disease or other health conditions affected by alcohol consumption
People who are driving or operating machinery
Those with a known allergy or sensitivity to agave-based spirits
Individuals following religions or lifestyles that prohibit alcohol consumption
People with a history of alcohol-induced migraines or severe hangovers
Those on a strict calorie-controlled diet (due to the caloric content of alcohol)
Individuals with certain gastrointestinal conditions that may be aggravated by alcohol
People with compromised immune systems
Those who are about to engage in activities requiring full mental alertness
Individuals with a family history of alcoholism who may be at higher risk for developing alcohol dependencyRemember, it’s always best to consult with a healthcare professional for personalized advice regarding alcohol consumption, especially if you have any health concerns or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.