Traditional nigiri sushi is typically gluten-free, as it consists of raw fish placed on top of vinegared rice. However, some variations may include ingredients containing gluten, such as soy sauce or certain marinades, so it’s always best to check with the chef or restaurant to confirm if you have gluten sensitivities.

High-quality protein: The fish used in Nigiri provides lean protein, essential for muscle growth and repair.
Omega-3 fatty acids: Many fish used in Nigiri (like salmon and tuna) are rich in omega-3s, which support heart and brain health.
Low in calories: Nigiri is generally a low-calorie food option, making it suitable for weight management.
Rich in vitamins: Fish contains vitamins like B12, D, and A, which are important for various bodily functions.
Mineral content: Nigiri often provides minerals like selenium, zinc, and iodine, which support immune function and thyroid health.
Antioxidants: Some fish used in Nigiri contain antioxidants that help combat oxidative stress in the body.
Digestive health: The vinegared rice in Nigiri can support digestive health due to its probiotic properties.
Low in saturated fat: Compared to many other protein sources, the fish in Nigiri is typically low in saturated fat.
Supports thyroid function: The iodine content in seafood can help maintain proper thyroid function.
Promotes satiety: The combination of protein and carbohydrates in Nigiri can help you feel full and satisfied.Remember that the health benefits can vary depending on the type of fish used and how the Nigiri is prepared.
Pregnant women, due to the risk of foodborne illnesses that could harm the fetus
Young children, especially those under 5, as their immune systems are still developing
Elderly individuals, who may have weakened immune systems
People with compromised immune systems, such as those undergoing chemotherapy or with HIV/AIDS
Individuals with liver disease or decreased liver function
Those with a history of alcohol abuse, as their livers may be more susceptible to parasites
People with certain blood disorders, such as hemochromatosis
Individuals allergic to fish or shellfish
Those taking medications that suppress the immune system
People with a history of foodborne illnesses or who are particularly susceptible to them
Individuals who have recently undergone surgery or have open wounds
Those with chronic illnesses that affect the digestive system or immune responseRemember, it’s always best to consult with a healthcare provider for personalized advice based on individual health conditions and circumstances.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.