Is Oat flour Gluten Free?
Oat flour is naturally gluten-free, but it can often be contaminated with gluten during growing or processing due to cross-contact with wheat, barley, or rye. To ensure gluten-free oat flour, look for products specifically labeled as gluten-free, which means they’ve been processed in dedicated gluten-free facilities and tested to contain less than 20 parts per million of gluten.

Gluten-free option for those with celiac disease or gluten sensitivity
High in fiber, which aids digestion and promotes feelings of fullness
Rich in protein compared to other grain flours
Contains beta-glucan, a soluble fiber that may help lower cholesterol levels
Provides essential minerals like iron, magnesium, and zinc
Low glycemic index, which can help regulate blood sugar levels
Contains antioxidants, including avenanthramides, which have anti-inflammatory properties
Supports heart health due to its fiber and nutrient content
May help with weight management by promoting satiety
Easy to make at home by grinding rolled oats
Often more affordable than other specialty flours
Adds nutritional value to recipes when used as a substitute for all-purpose flour
People with celiac disease or non-celiac gluten sensitivity, unless the oat flour is certified gluten-free
Individuals with oat allergies or sensitivities
Those following a grain-free or paleo diet
People on a low-carb or ketogenic diet, due to oat flour’s higher carbohydrate content
Individuals with avenin sensitivity (a protein found in oats that can cause reactions in some people)
Those with digestive issues who may be sensitive to the fiber content in oats
People following a low FODMAP diet, as oats can be high in FODMAPs for some individuals
Anyone advised by their healthcare provider to avoid oats or oat products for specific health reasons
Those with cross-reactivity to oats due to wheat or other grain allergies
Individuals trying to manage blood sugar levels, as oat flour can have a higher glycemic index compared to some other floursRemember that it’s always best to consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have specific health concerns or dietary restrictions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.