Is Oat Gluten Free?
Oats themselves are naturally gluten-free. However, due to potential cross-contamination during growing or processing, not all oat products are guaranteed to be gluten-free unless specifically labeled as such.

Rich in antioxidants, particularly avenanthramides, which may help lower blood pressure
High in fiber, especially beta-glucan, which can reduce cholesterol levels and improve heart health
May help control blood sugar levels, beneficial for people with diabetes
Promotes feelings of fullness, which can aid in weight management
Contains important vitamins and minerals, including manganese, phosphorus, copper, iron, zinc, and B vitamins
May reduce the risk of childhood asthma when introduced early in a child’s diet
Supports digestive health due to its high fiber content
Potentially lowers the risk of colorectal cancer
Helps in skin care when applied topically, soothing irritation and itching
May boost immune system function
Provides a good source of complex carbohydrates for sustained energy
Gluten-free (when certified), making it suitable for people with celiac disease or gluten sensitivity
May help reduce inflammation in the body
Supports healthy gut bacteria due to its prebiotic properties
Potentially aids in reducing the risk of heart diseaseRemember, while oats offer many health benefits, they should be part of a balanced diet for optimal health.
People with celiac disease, as oats can be cross-contaminated with gluten during processing
Individuals with gluten sensitivity or intolerance, unless consuming certified gluten-free oats
Those with oat allergies or sensitivities
People with avenin sensitivity (a protein found in oats)
Individuals following a grain-free diet, such as the Paleo diet
Those on a low-carb or ketogenic diet, due to the carbohydrate content in oats
People with diabetes who need to carefully monitor their carbohydrate intake (should consult with a healthcare provider)
Individuals with digestive disorders like irritable bowel syndrome (IBS) who find that oats trigger symptoms
Those following a specific elimination diet as advised by a healthcare professional
People with difficulty swallowing or chewing, particularly when consuming whole oatsRemember that everyone’s dietary needs are different, and it’s always best to consult with a healthcare provider or registered dietitian before making significant changes to your diet.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.