Oats themselves are naturally gluten-free. However, oats are often processed in facilities that also handle wheat, barley, and rye, which can lead to cross-contamination, so people with celiac disease or gluten sensitivity should look for certified gluten-free oats to ensure they are safe to consume.

Rich in antioxidants, particularly avenanthramides
High in fiber, especially beta-glucan, which aids digestion
May help lower cholesterol levels
Can improve blood sugar control
Promotes feelings of fullness, which may aid in weight management
Good source of important vitamins and minerals, including manganese, phosphorus, copper, iron, zinc, folate, and B vitamins
May reduce the risk of childhood asthma
Can help relieve constipation
Supports healthy gut bacteria
May help reduce the risk of heart disease
Contains compounds that may help reduce blood pressure
Gluten-free (when processed in a gluten-free facility), making them suitable for people with celiac disease or gluten sensitivity
May enhance immune system defenses against bacterial infections
Could help reduce the risk of certain types of cancer, particularly colon cancer
May help soothe skin conditions when applied topically
Potentially beneficial for reducing inflammation in the body
People with celiac disease: Oats can be contaminated with gluten during processing, which can trigger symptoms in those with celiac disease.
Individuals with gluten sensitivity: Some people with non-celiac gluten sensitivity may also react to oats.
Those with oat allergies: A small percentage of people are allergic to oats and should avoid them completely.
People with avenin sensitivity: Avenin is a protein in oats that some individuals may be sensitive to, even if they don’t have celiac disease.
Individuals on a low FODMAP diet: Oats contain FODMAPs, which can trigger digestive issues in some people with IBS or other digestive disorders.
Those with digestive issues: Some people may find that oats exacerbate their digestive problems, such as bloating or gas.
Individuals with skin conditions: In rare cases, oats may trigger skin reactions in people with certain skin disorders.
People on specific low-carb diets: Oats are relatively high in carbohydrates, which may not fit into some restrictive low-carb diet plans.
Those with beta-glucan sensitivity: Some individuals may be sensitive to beta-glucan, a type of fiber found in oats.It’s important to note that many of these issues are rare, and oats are generally considered a healthy food for most people. Always consult with a healthcare professional if you have concerns about including oats in your diet.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.