Generally, plain orange-flavored Jello and most other Jello products are gluten-free. However, it’s always best to check the specific product’s ingredient list and packaging for any gluten-containing additives or potential cross-contamination warnings, especially if you have celiac disease or severe gluten sensitivity.

Low in calories: Orange Jello is generally low in calories, making it a potential option for those watching their calorie intake.
Hydration: Jello is mostly water, which can contribute to daily fluid intake and hydration.
Protein source: Gelatin, the main ingredient in Jello, is a source of protein, though the amount is minimal.
Potential digestive benefits: Some people find that gelatin can help soothe digestive issues.
Vitamin C: If made with real orange juice or fortified, it may contain some vitamin C, which supports immune function.
Easy to consume: For individuals with difficulty swallowing, Jello can be an easy-to-eat food option.
Mood booster: The bright color and sweet taste may provide a psychological boost for some people.
Low in fat: Orange Jello is typically fat-free.It’s important to note that these benefits are limited, and Orange Jello should not be considered a health food. It’s high in sugar and artificial ingredients, so it should be consumed in moderation as part of a balanced diet.
People with phenylketonuria (PKU): Jello often contains aspartame, which can be harmful to those with PKU.
Individuals with gelatin allergies: Jello is primarily made of gelatin, which can cause allergic reactions in some people.
Those following a vegan or vegetarian diet: Gelatin is derived from animal products, making jello unsuitable for these diets.
People with diabetes: Sugar-free versions may be an option, but regular jello can cause blood sugar spikes.
Individuals on a low-sugar diet: Regular jello contains added sugars.
Those with certain religious dietary restrictions: Some religions prohibit the consumption of gelatin derived from certain animals.
People with digestive sensitivities: Some may find jello difficult to digest.
Individuals on a low-calorie diet: While not high in calories, jello may not be the most nutrient-dense option.
Those with artificial dye sensitivities: Orange jello often contains artificial coloring.Always consult with a healthcare professional for personalized dietary advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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