Panera Bread offers some gluten-free menu items, but they are not a fully gluten-free establishment. While they have options like salads and soups that can be made gluten-free, their kitchen is not a dedicated gluten-free facility, so there is a risk of cross-contamination for those with celiac disease or severe gluten sensitivities.

Fresh ingredients: Panera uses fresh, high-quality ingredients in many of their dishes.
Whole grain options: They offer whole grain bread and bakery items, which can provide more fiber and nutrients than refined grains.
Salad choices: Panera has a variety of salads that can be a good source of vegetables and nutrients.
Lean protein options: Many menu items include lean proteins like chicken, turkey, and plant-based proteins.
Soup options: Some of their soups can be nutritious and relatively low in calories.
Transparency: Panera provides nutritional information for their menu items, allowing customers to make informed choices.
Customization: Customers can often modify menu items to fit their dietary needs or preferences.
Lower calorie options: Panera offers some lower calorie menu items for those watching their calorie intake.
Vegetarian and vegan choices: There are several plant-based options available for those following vegetarian or vegan diets.
Reduced sodium options: Some menu items are designed to be lower in sodium.
Antibiotic-free meat: Panera uses chicken and turkey raised without antibiotics.
No artificial preservatives: The company has committed to removing artificial preservatives from their food.Remember that the healthiness of a meal at Panera (or any restaurant) ultimately depends on the specific items ordered and portion sizes consumed.
Individuals with severe gluten allergies or celiac disease: While Panera offers some gluten-free options, cross-contamination is possible in their kitchens.
People with severe nut allergies: Panera uses nuts in several menu items, and cross-contamination is possible.
Those on strict low-carb or ketogenic diets: Many of Panera’s menu items are high in carbohydrates.
Individuals with dairy allergies: Panera uses dairy products in many of their menu items.
People on very tight budgets: Panera is often considered more expensive than some fast-food alternatives.
Those seeking vegan options: While Panera has some vegetarian choices, strict vegan options are limited.
Individuals with soy allergies: Panera uses soy in some of their products.
People with egg allergies: Many baked goods and some other menu items contain eggs.
Those looking for extensive organic or non-GMO options: While Panera has made efforts to remove artificial ingredients, not all items are organic or non-GMO.
Individuals with specific religious dietary restrictions: Some menu items may not meet certain religious dietary laws.Remember, many of these concerns can be addressed by carefully reviewing the menu, asking staff about ingredients, or checking Panera’s allergen information online before dining.
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What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
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This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
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Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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