Panko breadcrumbs are traditionally made from wheat bread, which contains gluten, so standard panko is not gluten-free. However, there are now gluten-free panko alternatives available on the market, made from rice or other gluten-free grains, for those who need to avoid gluten in their diet.

Lower calorie content compared to regular breadcrumbs
Less oil absorption during frying, resulting in a lighter, less greasy dish
Lower sodium content than many seasoned breadcrumbs
Crispier texture, which may lead to greater satisfaction with smaller portions
No added sugar, unlike some commercial breadcrumbs
Can be used to create a crispy coating on baked dishes, reducing the need for frying
Versatile ingredient that can encourage consumption of healthier foods like fish and vegetables
Often made from wheat flour, which provides some B vitamins and mineralsIt’s important to note that while panko itself isn’t particularly nutritious, its main benefits come from how it’s used in cooking and its potential to make healthier dishes more appealing.
Individuals with celiac disease or gluten sensitivity, as Panko is typically made from wheat flour
People following a gluten-free diet for other health reasons
Those with wheat allergies
Individuals on low-carb or ketogenic diets, due to the high carbohydrate content
People trying to reduce their calorie intake, as Panko adds extra calories to dishes
Those with diabetes who need to carefully monitor their carbohydrate intake
Individuals following a paleo or grain-free diet
People with certain autoimmune conditions who may benefit from avoiding gluten
Those adhering to a raw food diet, as Panko is a processed food ingredient
Individuals with specific dietary restrictions that exclude bread productsRemember that while these groups should generally avoid Panko, individual dietary needs can vary. It’s always best to consult with a healthcare professional or registered dietitian for personalized advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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