Parmesan cheese is naturally gluten-free as it is made from milk, salt, and rennet, which do not contain gluten. However, it’s important to check the label or with the manufacturer to ensure no gluten-containing additives have been used and that there is no risk of cross-contamination during production.

High in protein: Parmesan is an excellent source of protein, which is essential for muscle growth and repair.
Rich in calcium: It provides a significant amount of calcium, which is crucial for bone health and strength.
Contains phosphorus: This mineral works with calcium to build strong bones and teeth.
Good source of vitamins: Parmesan contains vitamins A, B6, and B12, which support various bodily functions.
Provides zinc: Zinc is important for immune function and wound healing.
Contains probiotics: Some types of Parmesan contain beneficial bacteria that can support gut health.
Low in lactose: It’s naturally low in lactose, making it more tolerable for some people with lactose sensitivity.
Contains conjugated linoleic acid (CLA): This fatty acid may have anti-inflammatory properties.
Provides selenium: An antioxidant that supports thyroid function and helps protect cells from damage.
Contains easily digestible fats: The fats in Parmesan are mostly short-chain, which are easier for the body to break down.
Umami flavor: Its strong flavor can enhance the taste of dishes, potentially reducing the need for added salt.Remember that while Parmesan has these benefits, it’s also high in sodium and calories, so it should be consumed in moderation as part of a balanced diet.
Individuals with dairy allergies or severe lactose intolerance
People following a vegan diet
Those with milk protein allergies
Individuals on a low-sodium diet (Parmesan is relatively high in sodium)
People with galactosemia (a rare genetic disorder that affects how the body processes galactose)
Those following a strict kosher diet (if the Parmesan is not certified kosher)
Individuals with a history of calcium oxalate kidney stones (due to high calcium content)
People on certain antibiotics that interact with tyramine (found in aged cheeses like Parmesan)
Those taking MAO inhibitors (a type of antidepressant that interacts with tyramine)
Individuals with histamine intolerance (aged cheeses can be high in histamine)
People trying to avoid or reduce animal products in their dietRemember, it’s always best to consult with a healthcare professional or registered dietitian for personalized advice regarding dietary restrictions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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