Parmesan cheese is naturally gluten-free, as it is made from milk, salt, and rennet, none of which contain gluten. However, it’s important to check the label or confirm with the manufacturer, as some low-quality or processed versions might contain gluten-containing additives or be produced in facilities that handle gluten products, potentially leading to cross-contamination.

High in protein: Parmesan is an excellent source of protein, which is essential for muscle growth and repair.
Rich in calcium: It provides a significant amount of calcium, important for strong bones and teeth.
Contains phosphorus: This mineral works with calcium to build and maintain bone health.
Good source of vitamin A: Beneficial for eye health, immune function, and skin health.
Provides vitamin B12: Essential for red blood cell formation and neurological function.
Contains zinc: Important for immune function, wound healing, and DNA synthesis.
Low in lactose: Easier to digest for people with mild lactose intolerance.
Contains probiotics: Some varieties may contain beneficial bacteria that support gut health.
Rich in flavor: Its strong taste means a little goes a long way, potentially helping with portion control.
Contains conjugated linoleic acid (CLA): May have anti-inflammatory properties and potential benefits for heart health.
Provides selenium: An antioxidant that supports thyroid function and helps protect cells from damage.
Contains riboflavin (vitamin B2): Important for energy metabolism and cellular function.Remember, while Parmesan cheese has these benefits, it’s also high in sodium and calories, so it should be consumed in moderation as part of a balanced diet.
Individuals with severe dairy allergies
People with lactose intolerance (although Parmesan is very low in lactose)
Those following a vegan diet
People with milk protein allergies
Individuals on a low-sodium diet (Parmesan is relatively high in sodium)
Those with galactosemia (a rare genetic disorder)
People following a kosher diet that prohibits mixing meat and dairy
Individuals with certain types of migraines triggered by aged cheeses
Those on a very low-fat diet (Parmesan is high in fat)
People with histamine intolerance (Parmesan is high in histamines)
Individuals following specific religious or cultural dietary restrictions that exclude dairy productsRemember, it’s always best to consult with a healthcare professional or registered dietitian for personalized dietary advice.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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