Pearl barley is not gluten-free as it contains gluten proteins. Individuals with celiac disease or gluten sensitivity should avoid pearl barley and opt for gluten-free alternatives like quinoa, rice, or buckwheat instead.

High in fiber: Promotes digestive health and helps maintain regular bowel movements
Low glycemic index: Helps regulate blood sugar levels and may benefit those with diabetes
Rich in vitamins and minerals: Particularly B vitamins, iron, magnesium, and selenium
Contains antioxidants: May help protect against cellular damage and reduce inflammation
Supports heart health: The fiber and beta-glucans may help lower cholesterol levels
Aids in weight management: The high fiber content promotes feelings of fullness
Provides sustained energy: Complex carbohydrates offer long-lasting energy
Supports bone health: Contains phosphorus and copper, which are important for bone formation
May reduce the risk of gallstones: Regular consumption is associated with lower gallstone risk
Supports immune function: Contains selenium, which plays a role in immune system health
Versatile and easy to incorporate into various dishes: Can be used in soups, stews, salads, and as a rice substituteRemember that while pearl barley offers these benefits, it’s important to consume it as part of a balanced diet for optimal health.
Those with celiac disease or gluten sensitivity, as pearl barley contains gluten
Individuals with a wheat allergy, as there may be cross-contamination concerns
People following a strict gluten-free diet for any reason
Those with grain allergies or intolerances
Individuals on a low-carb or ketogenic diet, due to barley’s high carbohydrate content
People with certain gastrointestinal conditions that require a low-fiber diet
Those with a specific allergy to barley
Individuals following a paleo or grain-free diet
People with difficulty digesting FODMAPs (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols)
Anyone who has been advised by their healthcare provider to avoid barley or similar grainsRemember, it’s always best to consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have specific health concerns or dietary restrictions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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