Is Pearled Barley Gluten Free?
Pearled barley is not gluten-free as it contains gluten proteins. Barley is one of the three main gluten-containing grains, along with wheat and rye, making it unsuitable for those with celiac disease or gluten sensitivity.

High in fiber, promoting digestive health and regularity
May help lower cholesterol levels
Can aid in blood sugar control and improve insulin sensitivity
Rich in vitamins and minerals, particularly B vitamins and selenium
Contains antioxidants that may help reduce inflammation
May contribute to weight management due to its filling nature
Supports heart health by reducing risk factors for cardiovascular disease
Provides a good source of protein, especially for plant-based diets
May help reduce the risk of certain types of cancer, particularly colon cancer
Supports bone health due to its phosphorus and copper content
Can contribute to a healthy immune system
May help reduce blood pressure
Provides sustained energy due to its complex carbohydrates
Gluten-free option available (if processed in a gluten-free facility), suitable for those with gluten sensitivitiesRemember that while pearled barley has many health benefits, it has had some of its bran removed, so it’s not quite as nutritious as whole grain barley. However, it still offers significant nutritional value and health benefits.
People with celiac disease: Barley contains gluten, which can trigger symptoms in those with celiac disease.
Individuals with non-celiac gluten sensitivity: Some people experience adverse reactions to gluten without having celiac disease.
Those with a wheat allergy: While barley is not wheat, cross-contamination can occur during processing, posing a risk for people with severe wheat allergies.
Individuals following a gluten-free diet: Barley is not suitable for strict gluten-free diets.
People with irritable bowel syndrome (IBS): Some individuals with IBS may find that barley exacerbates their symptoms.
Those on a low FODMAP diet: Barley is high in fructans, which are not well-tolerated on a low FODMAP diet.
Individuals with grain allergies: Some people may have specific allergies to barley or other grains.
People with certain digestive disorders: Those with inflammatory bowel diseases like Crohn’s disease or ulcerative colitis may need to limit or avoid barley, depending on their condition and symptoms.
Individuals on a low-carb or ketogenic diet: Barley is relatively high in carbohydrates and may not fit into these dietary plans.
Those with diabetes who are closely monitoring their carbohydrate intake: While barley has a lower glycemic index than some grains, it still contains carbohydrates that can affect blood sugar levels.Always consult with a healthcare professional or registered dietitian before making significant changes to your diet, especially if you have underlying health conditions.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.