Is Play Doh Gluten Free?
Play-Doh, the popular modeling compound, is not gluten-free as it contains wheat flour as one of its main ingredients. This means that individuals with celiac disease or gluten sensitivity should avoid handling or ingesting Play-Doh to prevent potential adverse reactions.

Fine motor skill development: Manipulating Play-Doh helps improve hand-eye coordination and dexterity in children.
Stress relief: Squeezing and molding Play-Doh can be a calming, stress-reducing activity for both children and adults.
Sensory stimulation: The texture and malleability of Play-Doh provide tactile sensory input, which can be beneficial for sensory processing.
Creativity and imagination: Using Play-Doh encourages creative thinking, which can contribute to overall mental well-being.
Hand strength: Kneading and shaping Play-Doh can help build hand and finger strength.
Emotional expression: Play-Doh can be used as a tool for emotional expression, potentially aiding in emotional regulation.
Social skills: When used in group settings, Play-Doh can encourage social interaction and cooperation.
Cognitive development: Creating shapes and objects with Play-Doh can aid in spatial awareness and problem-solving skills.
Aromatherapy: The distinct scent of Play-Doh can evoke positive memories and emotions for some people.It’s important to note that Play-Doh is not meant to be ingested and should be used under adult supervision for young children to ensure safety.
Infants and very young toddlers (under 3 years old) due to choking hazard
Children with wheat allergies, as Play-Doh contains wheat
Individuals with severe salt sensitivities, as Play-Doh contains salt
People with certain skin sensitivities or allergies to any of the ingredients
Those with open cuts or wounds on their hands
Individuals prone to putting non-food items in their mouths
People with compromised immune systems, if the Play-Doh is shared
Anyone allergic to specific fragrances or colors used in Play-Doh
Children or adults who have difficulty understanding not to eat Play-Doh
Pets, as ingestion can be harmful to animalsRemember that while Play-Doh is generally considered safe for most children and adults, it’s always best to supervise young children during play and follow the manufacturer’s guidelines for use.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.