Is Premier Protein Gluten Free?
Yes, Premier Protein products are generally gluten-free. However, it’s always best to check the specific product label or the company’s website for the most up-to-date information on allergens and ingredients for any particular Premier Protein item you’re interested in.

High protein content: Helps build and maintain muscle mass
Low in sugar: Supports blood sugar management and weight control
Low in fat: Aids in weight management and heart health
Good source of essential vitamins and minerals: Supports overall health and wellbeing
Convenient source of nutrition: Easy to consume on-the-go
Helps with satiety: Can reduce hunger and support weight management goals
Supports muscle recovery: Beneficial for athletes and active individuals
Gluten-free options: Suitable for those with gluten sensitivities or celiac disease
Low carbohydrate content: May be beneficial for those following low-carb diets
Can be used as a meal replacement: Helpful for weight management or busy lifestyles
Contains calcium: Supports bone health
May help maintain lean body mass: Especially important for older adults
Can contribute to daily protein intake: Helps meet recommended dietary allowances
Individuals with dairy allergies or severe lactose intolerance, as most Premier Protein products contain milk-based ingredients
People with soy allergies, as some Premier Protein products contain soy
Those with specific nut allergies, as some products may contain or be processed in facilities that handle nuts
Individuals with kidney problems or on dialysis, as high protein intake may be harmful
People with certain liver conditions, as processing excess protein can strain the liver
Individuals on certain medications that may interact with high protein intake
Pregnant or breastfeeding women, without first consulting their healthcare provider
Children, unless recommended by a pediatrician
People with phenylketonuria (PKU), as some products contain phenylalanine
Individuals with a history of gout or at high risk for gout
Those on strict, medically-supervised low-protein diets
People with certain gastrointestinal conditions that may be aggravated by protein supplements
Individuals with known sensitivities or allergies to any ingredients used in Premier Protein products.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.