Is Protein Powder Gluten Free?
Generally speaking, most pure protein powders are gluten-free, as they are typically made from sources like whey, casein, egg, pea, or rice protein which do not naturally contain gluten. However, it’s important to always check the label and ingredient list, as some protein powders may contain added ingredients that include gluten or may be processed in facilities that also handle gluten-containing products, potentially leading to cross-contamination.

Supports muscle growth and repair
Aids in weight management and satiety
Helps with post-workout recovery
Can supplement protein intake for those with dietary restrictions
May help maintain bone health
Supports healthy aging and preservation of lean body mass
Can boost metabolism
Provides essential amino acids for various bodily functions
May help control blood sugar levels
Can support immune system function
Convenient source of protein for busy lifestyles
May help reduce blood pressure
Can aid in wound healing
Supports hair, skin, and nail health
May help reduce inflammation in the bodyIt’s important to note that the specific benefits can vary depending on the type of protein powder (whey, casein, soy, pea, etc.) and individual health factors. Always consult with a healthcare professional before adding supplements to your diet.
People with kidney disease or reduced kidney function
Those with dairy allergies or lactose intolerance (for whey or casein-based protein powders)
Individuals with gout or at high risk for gout
People with certain inherited metabolic disorders (e.g., phenylketonuria for some protein powders)
Pregnant or breastfeeding women (unless approved by a healthcare provider)
Children and adolescents (unless recommended by a pediatrician)
Those taking certain medications that may interact with protein supplements
People with digestive disorders or sensitivities
Individuals with a history of eating disorders
Those who already consume adequate protein through their regular diet
People with liver disease or reduced liver function
Individuals with a history of calcium oxalate kidney stones
Those with certain hormone-sensitive conditions (for soy protein powders)
People allergic to specific ingredients commonly found in protein powdersIt’s always best to consult with a healthcare professional before adding protein powder or any supplement to your diet, especially if you have any pre-existing health conditions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
Asked Questions 1
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.