Is Pure Vanilla Extract Gluten Free?
Pure vanilla extract is typically gluten-free as it is made from vanilla beans, alcohol, and water, none of which contain gluten. However, it’s always best to check the label or contact the manufacturer to ensure there are no added ingredients or potential cross-contamination issues that could introduce gluten into the product.

Antioxidant properties: Vanilla contains vanillin, which has antioxidant effects that may help protect cells from damage caused by free radicals.
Anti-inflammatory effects: Some studies suggest vanilla may have anti-inflammatory properties, potentially helping to reduce inflammation in the body.
Mood enhancement: The scent of vanilla has been shown to have a calming effect and may help reduce stress and anxiety.
Potential anticancer properties: Some research indicates that vanillin may have anticancer effects, though more studies are needed.
Heart health: Vanilla extract contains small amounts of potassium, which is important for heart health and blood pressure regulation.
Antibacterial properties: Vanilla has shown some antibacterial effects, which may help fight certain harmful bacteria.
Digestive aid: Vanilla may help soothe an upset stomach and aid in digestion.
Skin health: When applied topically, vanilla extract may have benefits for skin health due to its antioxidant properties.
Weight management: The sweet aroma of vanilla may help reduce sugar cravings, potentially aiding in weight management efforts.
Oral health: Some studies suggest vanillin may have properties that help fight tooth decay and oral bacteria.Remember that while these benefits are promising, many require more research, and vanilla extract should be consumed in moderation as part of a balanced diet.
Individuals with vanilla allergies
People with alcohol sensitivities or those avoiding alcohol, as most vanilla extracts contain ethanol
Recovering alcoholics who want to avoid all products containing alcohol
Some individuals following certain religious dietary restrictions that prohibit alcohol consumption
Young children, in large amounts, due to the alcohol content
Pets, especially dogs, as vanilla extract can be toxic to them
Individuals on certain medications that interact negatively with alcohol
People with liver conditions who need to limit alcohol intake
Those following a very strict low-carb or ketogenic diet, as vanilla extract contains small amounts of carbohydrates
Individuals who are highly sensitive to caffeine, as vanilla extract contains trace amountsIt’s important to note that for most people, the small amounts of vanilla extract typically used in cooking and baking are generally safe. However, these groups may need to exercise caution or seek alternatives.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.