Is Rice Bran Gluten Free?
Rice bran is naturally gluten-free as it comes from rice, which does not contain gluten. However, it’s important to check product labels or verify with manufacturers to ensure there’s no cross-contamination during processing, especially if you have celiac disease or severe gluten sensitivity.

Rich in antioxidants: Contains powerful antioxidants like oryzanol, tocotrienols, and ferulic acid
Heart health: May help lower cholesterol levels and reduce the risk of cardiovascular disease
Blood sugar control: Can help regulate blood sugar levels, beneficial for diabetics
Weight management: High fiber content promotes feelings of fullness and may aid in weight loss
Digestive health: Fiber content supports healthy digestion and regular bowel movements
Cancer prevention: Some studies suggest potential anti-cancer properties
Immune system support: Contains nutrients that may boost immune function
Skin health: Rich in vitamins and antioxidants that can promote healthy skin
Bone health: Contains minerals like calcium and magnesium that support bone density
Anti-inflammatory properties: May help reduce inflammation in the body
Liver health: Some studies indicate potential liver-protective effects
Energy boost: Rich in B-vitamins that help convert food into energy
Brain health: Contains nutrients that may support cognitive function
Hormone balance: May help balance hormones, particularly in menopausal womenRemember that while rice bran offers these potential benefits, it’s always best to consult with a healthcare professional before making significant changes to your diet.
People with celiac disease or gluten sensitivity: While rice bran itself is gluten-free, cross-contamination during processing may occur.
Individuals with digestive issues: Rice bran is high in fiber and may exacerbate symptoms for those with irritable bowel syndrome (IBS) or other digestive disorders.
People taking certain medications: Rice bran may interfere with the absorption of some medications, including blood thinners like warfarin.
Those with a history of kidney stones: Rice bran is high in oxalates, which can contribute to kidney stone formation in susceptible individuals.
People with iron deficiency: Rice bran contains phytic acid, which can inhibit iron absorption.
Individuals with compromised immune systems: Raw or unprocessed rice bran may contain harmful bacteria.
Those on a low-fiber diet: Rice bran is high in fiber and may not be suitable for people who need to limit their fiber intake.
People with rice allergies: Although rare, some individuals may be allergic to rice and its byproducts.
Those on calorie-restricted diets: Rice bran is calorie-dense and may not fit into some weight loss plans.
Individuals with mineral imbalances: Rice bran can affect the absorption of certain minerals, potentially exacerbating existing imbalances.Always consult with a healthcare professional before making significant changes to your diet, especially if you have pre-existing health conditions or concerns.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.