Is Rice Bran Oil Gluten Free?
Yes, rice bran oil is gluten-free. It is derived from the outer layer of rice grains and does not contain any wheat, barley, rye, or other gluten-containing ingredients.

Low in saturated fat and high in monounsaturated and polyunsaturated fats, promoting heart health
Contains gamma-oryzanol, which can help lower cholesterol levels
Rich in antioxidants, including vitamin E and tocotrienols, which may help reduce inflammation and oxidative stress
May help improve insulin sensitivity and blood sugar control
Contains plant sterols, which can help reduce cholesterol absorption in the gut
High smoke point, making it suitable for high-temperature cooking while preserving its nutritional value
May help improve skin health due to its antioxidant and moisturizing properties
Contains squalene, which may have anti-cancer properties
May help reduce menopausal symptoms due to its gamma-oryzanol content
Potentially beneficial for liver health due to its antioxidant properties
May help support immune function through its vitamin E content
Could aid in weight management by promoting feelings of fullness
May have anti-inflammatory effects, potentially benefiting conditions like arthritisRemember that while rice bran oil has many potential health benefits, it should be consumed as part of a balanced diet and healthy lifestyle.
People with allergies to rice or rice products: Although rare, some individuals may have an allergic reaction to rice bran oil.
Those with sensitive digestive systems: Some people may experience digestive discomfort due to the high fiber content in rice bran oil.
Individuals on blood-thinning medications: Rice bran oil contains vitamin K, which can interfere with blood-thinning medications like warfarin.
People with a history of gallstones: The high content of plant sterols in rice bran oil might increase the risk of gallstone formation in susceptible individuals.
Those with specific health conditions: People with certain medical conditions should consult their healthcare provider before incorporating rice bran oil into their diet.
Individuals on a low-fat diet: Rice bran oil, like all oils, is high in calories and fat, which may not be suitable for those on strict low-fat diets.
People with concerns about arsenic exposure: Rice products, including rice bran oil, may contain trace amounts of arsenic, which could be a concern for some individuals.It’s always best to consult with a healthcare professional before making significant changes to your diet, especially if you have any health concerns or are taking medications.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently Asked Questions
Our Expert
Drs. Ilse van Asperen
Drs. Ilse van Asperen is a medical doctor specialising in orthomolecular therapy and nutritional coaching. With a background in public and clinical health research and management, she focuses on addressing the root causes of health issues through diet, gut health, and stress reduction. As a professional editor for Little Helpers, she reviews all gluten-free content to ensure accuracy, safety, and scientific credibility. More about me
Our Sources
The information on this page is based on reputable health and nutrition organisations, ensuring accuracy and reliability for anyone following a gluten-free diet. For further details, see the sources below.
Sources
Experiences of our customers
Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.