Is Sake Gluten Free?
Generally, sake is considered gluten-free as it is made from rice, water, yeast, and koji (a type of mold). However, some sake producers may add small amounts of distilled alcohol or other ingredients that could potentially contain gluten, so it’s always best to check with the specific brand or manufacturer if you have celiac disease or severe gluten sensitivity.

Low calorie content compared to many other alcoholic beverages
Contains amino acids that may help improve skin quality
Rich in ferulic acid, an antioxidant with potential anti-aging properties
Contains enzymes that may aid digestion
Typically gluten-free, making it suitable for those with gluten sensitivities
Lower acidity compared to wine, which may be beneficial for those with acid reflux
Contains kojic acid, which may have skin-lightening properties
May have antimicrobial properties
Traditionally used in Japan for its purported moisturizing effects on skin when applied topically
May help reduce stress and promote relaxation when consumed in moderationRemember, while sake may offer these potential benefits, it’s important to consume alcohol in moderation, as excessive drinking can lead to numerous health problems.
Pregnant women: Like all alcoholic beverages, sake should be avoided during pregnancy to prevent potential harm to the developing fetus.
Individuals with alcohol use disorder or those in recovery: Sake contains alcohol and can trigger relapse or exacerbate existing alcohol-related issues.
People taking certain medications: Some medications can interact negatively with alcohol, including sake. Always consult with a healthcare provider about potential interactions.
Individuals with liver disease or other liver problems: Alcohol can further damage the liver in these cases.
Those with allergies to rice or any ingredients used in sake production: Some people may have sensitivities to components in sake.
People with gout: Sake can potentially trigger gout flare-ups in susceptible individuals.
Individuals with a history of pancreatitis: Alcohol consumption can increase the risk of pancreatitis attacks.
Those with certain religious or cultural restrictions on alcohol consumption.
Individuals under the legal drinking age in their respective countries.
People operating vehicles or heavy machinery: Sake impairs judgment and reflexes like other alcoholic beverages.Remember, it’s always best to consult with a healthcare professional for personalized advice regarding alcohol consumption.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.