Is Sesame Seed Gluten Free?
Yes, sesame seeds are naturally gluten-free. They are safe for people with celiac disease or gluten sensitivity to consume, as long as they haven’t been cross-contaminated with gluten-containing products during processing or packaging.

Rich in antioxidants, particularly sesamin and sesamolin
May help lower cholesterol levels
Potential to reduce high blood pressure
Good source of fiber, supporting digestive health
Contains lignans, which may help prevent certain cancers
High in calcium, promoting bone health
Provides iron, supporting red blood cell production
Contains zinc, important for immune function and wound healing
Rich in magnesium, supporting muscle and nerve function
May help regulate blood sugar levels
Contains vitamin E, an antioxidant that supports skin health
Potential anti-inflammatory properties
May help reduce arthritis pain
Supports hormone balance, particularly in post-menopausal women
Contains B vitamins, important for metabolism and energy production
May improve sleep quality due to tryptophan content
Potential to support liver health
Can aid in weight management as part of a balanced dietRemember to consult with a healthcare professional before making significant changes to your diet or if you have specific health concerns.
People with a known sesame allergy
Individuals with a history of anaphylaxis to other seeds or nuts (as there may be cross-reactivity)
Those who are undergoing allergy testing or following an elimination diet to identify food sensitivities
People taking blood-thinning medications (such as warfarin) without consulting their doctor, as sesame seeds contain vitamin K which can interfere with these medications
Individuals with digestive disorders like diverticulitis, as small seeds may irritate the digestive tract
Those with a history of kidney stones, as sesame seeds are high in oxalates
People on a low-calorie or low-fat diet, as sesame seeds are calorie-dense and high in fat
Individuals with compromised immune systems, who should be cautious with raw sesame seeds due to potential contamination
Those preparing for certain medical procedures or surgeries, as directed by their healthcare provider
Young children under 3 years old, due to potential choking hazards (whole seeds)Always consult with a healthcare professional or allergist if you have concerns about consuming sesame seeds.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
100% Tolerase® G Anti-Gluten Pills

Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

Frequently
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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.