Is Spent Grain Gluten Free?
Spent grain, which is the leftover malt and adjuncts after the mashing process in beer brewing, typically contains gluten unless it comes from naturally gluten-free grains. Therefore, most spent grain is not gluten-free, as it usually originates from barley, wheat, or other gluten-containing grains used in beer production.

High in fiber: Spent grain is an excellent source of dietary fiber, which aids digestion, promotes regular bowel movements, and helps maintain gut health.
Protein-rich: It contains a significant amount of protein, which is essential for muscle growth, repair, and overall body function.
Low in calories: Spent grain is relatively low in calories, making it a good option for those watching their caloric intake.
Rich in B vitamins: It contains various B vitamins, including niacin, thiamin, and riboflavin, which are important for energy metabolism and overall health.
Source of minerals: Spent grain provides minerals such as phosphorus, magnesium, and selenium, which are essential for various bodily functions.
Antioxidant properties: It contains antioxidants that help protect cells from damage caused by free radicals.
Potential prebiotic effects: The fiber in spent grain may act as a prebiotic, promoting the growth of beneficial gut bacteria.
May help lower cholesterol: The high fiber content may contribute to reducing cholesterol levels in the blood.
Supports weight management: The combination of high fiber and protein can help increase satiety and potentially aid in weight management.
Sustainable nutrition: Using spent grain as a food source reduces waste and provides a sustainable way to obtain nutrients.Remember that while spent grain offers these potential benefits, it’s important to incorporate it into a balanced diet and consult with a healthcare professional before making significant dietary changes.
People with celiac disease or gluten intolerance: Spent grain still contains gluten proteins, which can cause adverse reactions in these individuals.
Those with grain allergies: If you’re allergic to the specific grain used (usually barley, but sometimes wheat or rye), you should avoid spent grain.
Individuals with sensitive digestive systems: The high fiber content in spent grain might cause digestive discomfort for some people.
People on low-fiber diets: Due to its high fiber content, spent grain may not be suitable for those who need to limit their fiber intake for medical reasons.
Individuals with compromised immune systems: If the spent grain hasn’t been properly stored or handled, there’s a risk of bacterial growth, which could be dangerous for immunocompromised people.
Those with certain chronic conditions: People with conditions that require careful monitoring of nutrient intake (like kidney disease) should consult their healthcare provider before adding spent grain to their diet.
Pregnant women: As with any new food during pregnancy, it’s best to consult with a healthcare provider before consuming spent grain.
Young children: The high fiber content might be difficult for young digestive systems to process.Always consult with a healthcare professional if you have any concerns about adding spent grain to your diet.
Explore gluten management solutions like Tolerase® G.
What is Tolerase® G?
A new Approach for People with Gluten Sensitivity:
Explore the Science and Benefits of Tolerase® G.
Relief from Gluten Sensitivity
In the fight against gluten, there is a unique supplement that stands out: Little Helpers anti-gluten pills with 100% Tolerase® G.
This specific enzyme, Tolerase® G, a patented endopeptidase specific for proline, was developed by Royal DSM and has been scientifically proven to be effective in breaking down gluten residues ( 1) . Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP), an enzyme closely related to Tolerase® G, can break down gluten so effectively that it barely reaches the duodenum, potentially eliminating gluten toxicity ( 2) ( 3 ) .
On this page we explain why we are so enthusiastic about this supplement, supported by scientific research.

What is Gluten?
Gluten is a group of proteins found primarily in grains such as wheat, barley, and rye. These complex proteins give shape, strength, and texture to bread and other grain products. However, gluten is difficult to digest because it is rich in proline, a non-essential amino acid. This is why about 13% of the world’s population is sensitive to gluten in their diet (1).
How Tolerase® G Works
It is important to note that Tolerase G is designed to have optimal activity in the difficult conditions of the stomach. Its effectiveness on the digestion of gluten in the stomach and duodenum has been scientifically proven ( 1 ).
Studies have shown that a newly identified prolyl endoprotease derived from Aspergillus niger can effectively break down gluten proteins. This enzyme works optimally at a pH of 4–5, remains stable at pH 2, and is completely resistant to digestion by pepsin ( 2 ). Furthermore, research has shown that Aspergillus niger prolyl endoprotease (AN-PEP) accelerates the breakdown of gluten in the stomach so much that very little gluten reaches the duodenum ( 3 ). This suggests that co-administration of AN-PEP with a meal containing gluten could potentially eliminate gluten toxicity, allowing people to (occasionally) abandon their strict gluten-free diet ( 3 ).
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Unique Enzyme Solution
Discover how our 100% Tolerase® G pills help digest gluten and support your lifestyle in a clear video.
Little Helpers & Tolerase® G: Stronger Together in the Fight against Gluten.
At Little Helpers we are proud of our unique partnership with the producer of Tolerase® G DSM . Together we have spent 2.5 years of research and worked tirelessly to develop and perfect our gluten digestion pill, which contains 100% Tolerase® G.
Our shared commitment to quality and effectiveness has resulted in a product that is unmatched in the market. We have chosen to manufacture locally in Europe to ensure the highest quality standards and control.
Our pill has proven to be many times more effective than our competitors, and we offer it at the best price. We are convinced that our pill can make a difference for people who struggle with gluten sensitivity. That is why we encourage everyone to try it and experience the benefits for themselves!
The Only Effective Anti-Gluten Pills
Little Helpers Anti-Gluten Pills contain 100% Tolerase® G. Tolerase® G is the only enzyme on the market that has been scientifically proven to be effective enough to break down gluten in the stomach to the point where the body no longer reacts to it.

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Disclaimer: We do our best to provide accurate gluten information, but errors can happen. If you spot a mistake or have concerns, please contact us so we can make it right.